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The association between depressive symptoms and lower urinary tract symptoms and impact among women: Investigating behavioural, cognitive and physiological pathways.
Br J Health Psychol
February 2025
Division of Gerontology, Geriatrics, and Palliative Care, University of Alabama at Birmingham School of Medicine and Birmingham VA Medical Center, Birmingham, Alabama, USA.
Objective: Mechanistic studies are needed to understand why depressive symptoms are associated with poorer physical health. The objective of this study was to examine whether behavioural, cognitive and physiological factors mediated an association between depressive symptoms, measured in early adulthood, and lower urinary tract symptoms (LUTS) and their impact, a composite variable measured in mid-life adulthood, among women in the Coronary Artery Risk Development in Young Adults study, conducted in four regions of the United States.
Design: Prospective cohort study.
Gastric carcinoma leading to metastatic spinal cord compression.
J Pak Med Assoc
January 2025
Department of Oncology, Ziauddin University, Karachi, Pakistan.
Gastric cancer is described as a malignancy occurring in the region between the gastroesophageal junction and the pylorus. According to the histology, majority of gastric cancers are classified as adenocarcinomas. The prevalence of bone metastasis in the general population is 2-3%.
View Article and Find Full Text PDFImmunohistochemistry-based molecular subtypes of urothelial carcinoma derive different survival benefit from platinum chemotherapy.
J Pathol Clin Res
January 2025
Department of Urology, University of Duisburg-Essen, Essen, Germany.
Distinct molecular subtypes of muscle-invasive bladder cancer (MIBC) may show different platinum sensitivities. Currently available data were mostly generated at transcriptome level and have limited comparability to each other. We aimed to determine the platinum sensitivity of molecular subtypes by using the protein expression-based Lund Taxonomy.
View Article and Find Full Text PDFThe Effect of Life Activity Levels of Palliative Care Patients on the Caregivers' Perception of Caregivers Burden.
J Palliat Care
January 2025
Florence Nightingale Faculty of Nursing, Istanbul University-Cerrahpaşa, Department of Fundamentals of Nursing, Istanbul, Türkiye.
Studies show the effects of dependent patients' caregivers on the caregiving burden. Knowing the effects of maintenance of movement, especially in life activities, on the factors affecting the caregiving burden is important for the quality of care, ensuring that the caregiver's capacity is preserved. This descriptive and cross-sectional study research was carried out to determine the effect of life activity levels of palliative care patients on the care burden of caregivers.
View Article and Find Full Text PDFPREVENTion and treatment of incontinence-associated dermatitis through a codesigned manual (PREVENT-IAD): a study protocol for a feasibility cluster randomised controlled trial with a nested process evaluation.
BMJ Open
December 2024
School of Health Sciences, University of Southampton, Southampton, Hampshire, UK.
Introduction: Incontinence is commonly experienced by adults who receive care support in a residential facility or in their own home. These individuals are at risk of developing incontinence-associated dermatitis (IAD), which is caused by prolonged and repeated exposure of the skin to urine or faeces. An IAD manual was developed providing an evidence-based clinical algorithm and an e-learning training programme for the prevention and treatment of IAD.
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