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Heterogeneity in Mechanical Properties of Plant Cell Walls.
Plants (Basel)
December 2024
Shandong Laboratory of Advanced Agricultural Sciences at Weifang, Peking University Institute of Advanced Agricultural Sciences, Weifang 261000, China.
The acquisition and utilization of cell walls have fundamentally shaped the plant lifestyle. While the walls provide mechanical strength and enable plants to grow and occupy a three-dimensional space, successful sessile life also requires the walls to undergo dynamic modifications to accommodate size and shape changes accurately. Plant cell walls exhibit substantial mechanical heterogeneity due to the diverse polysaccharide composition and different development stages.
View Article and Find Full Text PDFATP-Binding Cassette and Solute Carrier Transporters: Understanding Their Mechanisms and Drug Modulation Through Structural and Modeling Approaches.
Pharmaceuticals (Basel)
November 2024
Inserm U1268 MCTR, CiTCoM UMR 8038 CNRS, Université Paris Cité, 75006 Paris, France.
The ATP-binding cassette (ABC) and solute carrier (SLC) transporters play pivotal roles in cellular transport mechanisms, influencing a wide range of physiological processes and impacting various medical conditions. Recent advancements in structural biology and computational modeling have provided significant insights into their function and regulation. This review provides an overview of the current knowledge of human ABC and SLC transporters, emphasizing their structural and functional relationships, transport mechanisms, and the contribution of computational approaches to their understanding.
View Article and Find Full Text PDFA Brief History of Cell Culture: From Harrison to Organs-on-a-Chip.
Cells
December 2024
Department of Genetic, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto 14040-904, Brazil.
This comprehensive overview of the historical milestones in cell culture underscores key breakthroughs that have shaped the field over time. It begins with Wilhelm Roux's seminal experiments in the 1880s, followed by the pioneering efforts of Ross Granville Harrison, who initiated groundbreaking experiments that fundamentally shaped the landscape of cell culture in the early 20th century. Carrel's influential contributions, notably the immortalization of chicken heart cells, have marked a significant advancement in cell culture techniques.
View Article and Find Full Text PDFAccessing the Lived Experiences of Children with Illness in Sweden for Health Care Research.
Children (Basel)
December 2024
Faculty of Caring Science, Work Life and Social Welfare, University of Borås, 50190 Borås, Sweden.
Background: Children are a relatively marginalized group when doing research in the context of illness, young children particularly so. This even though children can and should contribute their point of view in providing evidence-based care. This article contributes the experiences of Nurse Researchers in gathering research data in Sweden on the lived experiences of children undergoing needle-related medical procedures, living with home mechanical ventilation or undergoing treatment for cancer.
View Article and Find Full Text PDFAmbient Air Pollution Exposure and Breast Cancer Risk Worldwide: A Systematic Review of Longitudinal Studies.
Int J Environ Res Public Health
December 2024
College of Public Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Breast cancer is the most prevalent malignancy among women. Certain air pollutants have carcinogenic and estrogenic properties that can contribute to breast cancer development. This systematic review aimed to investigate the association between air pollution and breast cancer based on epidemiological evidence.
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