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Genomes reveal pervasive distant hybridization in nature among cyprinid fishes.
Gigascience
January 2025
State Key Laboratory of Developmental Biology of Freshwater Fish, Engineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, College of Life Sciences, Hunan Normal University, Changsha 410081, China.
Background: Genomic data have unveiled a fascinating aspect of the evolutionary past, showing that the mingling of different species through hybridization has left its mark on the histories of numerous life forms. However, the relationship between hybridization events and the origins of cyprinid fishes remains unclear.
Results: In this study, we generated de novo assembled genomes of 8 cyprinid fishes and conducted phylogenetic analyses on 24 species.
Chemoprevention Strategies for Precancerous Gastric Lesions Beyond Helicobacter pylori Eradication.
QJM
January 2025
Peking University Traditional Chinese Medicine Clinical Medical School (Xiyuan), Peking University Health Science Center, Beijing, 100091, People's Republic of China.
Gastric cancer (GC) is a significant global health challenge, particularly in high-incidence regions like East Asia. Despite improvements in screening and treatment, the progressive nature of precancerous lesions-such as atrophic gastritis, intestinal metaplasia, and dysplasia-necessitates effective prevention strategies. This review evaluates the role of chemoprevention in GC, focusing on agents designed to target these precancerous lesions.
View Article and Find Full Text PDFAlkalinity exposure induced growth inhibition, intestinal histopathological changes, and down-regulated nutrient transporter expression in Nile Tilapia: The ameliorative role of dietary camel whey protein hydrolysates.
Comp Biochem Physiol B Biochem Mol Biol
January 2025
Department of Aquatic Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt. Electronic address:
Alkaline stress impairs fish productivity and performance and, therefore, is considered one of the major challenges facing aquaculture. In this work, the effects of supplementing diets with camel whey protein hydrolysates (WPH) on growth, digestion, antioxidant capacity, and gene expression were investigated in Nile tilapia (Oreochromis niloticus) under alkaline stress. A total of 160 fish (16.
View Article and Find Full Text PDFDistal ileal volvulus leading to intestinal obstruction: A case report.
Int J Surg Case Rep
January 2025
Department of Diagnostic Radiology, BP Koirala Institute of Health Sciences (BPKIHS), Nepal.
Introduction: Small bowel volvulus (SBV) involves the abnormal twisting of a small bowel loop around its mesenteric axis, often causing intestinal obstruction. It is rare in Western countries but accounts for up to 20-35 % of small bowel obstruction (SBO) cases in Asia, Africa, and the Middle East due to dietary and environmental factors. Non specific symptoms might lead to delayed diagnosis.
View Article and Find Full Text PDFA Hepatic Oxidative Metabolite of Palmatine Ameliorates DSS-Induced Ulcerative Colitis by Regulating Macrophage Polarization Through AMPK/NF-κB Pathway.
Am J Chin Med
January 2025
School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, P. R. China.
Palmatine (PAL) and berberine are both classified as protoberberine alkaloids, derived from several traditional Chinese herbs such as Franch. and Schneid. These compounds are extensively used in treating dysentery and colitis.
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