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Decoding the SARS-CoV-2 Infection Process: Insights into Origin, Spread, and Therapeutic Approaches.
Microb Pathog
January 2025
Department of Bioengineering, Faculty of engineering, Integral University, Lucknow-226026, India. Electronic address:
Globally, over 768 million confirmed cases and 6.9 million deaths had been documented as of July 17, 2023. Coronaviruses have a relatively large RNA genome.
View Article and Find Full Text PDFOnline monitoring of water quality in industrial wastewater treatment process based on near-infrared spectroscopy.
Water Res
January 2025
NMPA Key Laboratory for Technology Research and Evaluation of Drug Products, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Shandong, Jinan 250012, China; Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Shandong, Jinan 250021, China; Key Laboratory of Chemical Biology (Ministry of Education), Shandong University, Shandong, Jinan 250012, China; Shandong Engineering Research Center for Transdermal Drug Delivery Systems, Shandong, Jinan 250098, China. Electronic address:
Water quality monitoring is one of the critical aspects of industrial wastewater treatment, which is important for checking the treatment effect, optimizing the treatment technology and ensuring that the water quality meets the standard. Chemical oxygen demand (COD) is a key indicator for monitoring water quality, which reflects the degree of organic matter pollution in water bodies. However, the current methods for determining COD values have drawbacks such as slow speed and complicated operation, which hardly meet the demand of online monitoring.
View Article and Find Full Text PDFHow Painful are Lumbar Hernias? A Comprehensive Review of Intervention Strategies.
Curr Pain Headache Rep
January 2025
Universidad de Alcalá, School of Medicine and Health Sciences, Department of Surgery, Medical and Social Sciences, Area of Human Anatomy and Embryology, Universidad de Alcalá, University Campus - C/ 19 Av de Madrid Km 33 600, 28871, Alcalá de Henares, Madrid, Spain.
Purpose Of Review: Low back pain (LBP) is considered an important issue of public health, with annual prevalence estimations almost achieving 60% of the worldwide population. Available treatments have a limited impact on this condition, although they allow to alleviate pain and recover the patient's quality of life. This review aims to go deeper on the understanding of this condition, providing an updated, brief, and concise whole picture of this common musculoskeletal problem.
View Article and Find Full Text PDFAnimal models of kabuki syndrome and their applicability to novel drug discovery.
Expert Opin Drug Discov
January 2025
Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.
Introduction: Kabuki Syndrome (KS) is a rare genetic disorder characterized by distinctive facial features, intellectual disability, and multiple congenital anomalies. It is caused by pathogenic variants in the and genes. Despite its significant disease burden, there are currently no approved therapies for KS, highlighting the need for advanced research and therapeutic development.
View Article and Find Full Text PDFAssessing the performance of ChatGPT in medical ethical decision-making: a comparative study with USMLE-based scenarios.
J Med Ethics
January 2025
Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.
Introduction: The integration of artificial intelligence (AI) into healthcare introduces innovative possibilities but raises ethical, legal and professional concerns. Assessing the performance of AI in core components of the United States Medical Licensing Examination (USMLE), such as communication skills, ethics, empathy and professionalism, is crucial. This study evaluates how well ChatGPT versions 3.
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