Five compounds have been isolated from the stems and leaves of Isodon albopilosus. On the basis of spectroscopic and chemical data, they were identified as macrocalyxin C, stearic acid, beta-sitosterol, ursolic acid and beta-sitosterol-beta-D-glucoside, respectively.
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Alboatisins A-C, ent-atisene diterpenoids from Isodon albopilosus.
J Nat Prod
June 2007
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
Three biogenetically interesting ent-kaurane-derived metabolites, alboatisins A-C (1-3), featuring a C-13-oxygenated ent-atisane skeleton, have been isolated from the aerial parts of Isodon albopilosus. Their structures were determined on the basis of spectroscopic evidence. Compound 2 exhibited cytotoxicity against A549 and HT-29 human cancer cells, with IC50 values of 8.
View Article and Find Full Text PDFent-Kaurane Diterpenoids from Isodon albopilosus.
J Nat Prod
December 2005
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
Nine new diterpenoids, albopilosins B-J (1-9), together with six known analogues, albopilosin A (10), macrocalyxin C (11), rabdokunmin C (12), excisanin (13), amethystonoic acid (14), and coetsanoic acid (15), were isolated from the aerial parts of Isodon albopilosus. The structures of 1-9 were established using spectroscopic methods including extensive 1D and 2D NMR analysis. The diterpenoids isolated were evaluated for their inhibitory activities against HepG2 (hepatoma) cells.
View Article and Find Full Text PDF[Chemical constituents of Isodon albopilosus (C.Y. Wu et H.W. Li) Hara].
Zhongguo Zhong Yao Za Zhi
April 1992
Five compounds have been isolated from the stems and leaves of Isodon albopilosus. On the basis of spectroscopic and chemical data, they were identified as macrocalyxin C, stearic acid, beta-sitosterol, ursolic acid and beta-sitosterol-beta-D-glucoside, respectively.
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