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Cryptogenic stroke and patent foramen ovale: endeavoring for clarity.
Front Neurol
January 2025
School of International Medicine, Istanbul Medipol University, Istanbul, Türkiye.
This review aims to summarize current knowledge and highlight recent findings on the association between cryptogenic stroke (CS) and patent foramen ovale (PFO). By presenting sometimes conflicting data, the review underscores the necessity for further research to clarify the complex mechanisms behind PFO-related CS and optimize its management. Results from research identifies specific conditions and scores, such as the risk of paradoxical embolism (RoPE) score, that help assess the likelihood of PFO-related cryptogenic stroke and guide treatment decisions.
View Article and Find Full Text PDFOptical transceivers serve as the backbone of high-speed data transmission over optical fiber in communication systems and there is a constant challenge to keep cost and power consumption low while increasing data capacities. However, dispersion impairments introduced by the transmission of data over optical fiber, limit the baud rates and fiber reach. In this paper, we demonstrate a low loss, transmission-based grating device to compensate for dispersion up to 20 km by the concatenation of gratings where the operation occurs outside of the stopband in the region where transmissivity is high, and the normal dispersion magnitude is large.
View Article and Find Full Text PDFImplementation of a clinical pathway for diabetes-related foot ulcers reduced the number of amputations and shortened hospital stay.
J Foot Ankle Res
March 2025
Department of Orthopaedic Surgery, Akershus University Hospital, Lørenskog, Norway.
Introduction: Diabetes-related foot ulcer (DFU) is the leading cause for lower extremity amputations (LEAs) in western countries, and may cause social isolation, depression, and death. However, people with DFU are not offered the same prioritized care as cancer patients, despite comparable mortality rates. We therefore decided to create a clinical pathway for patients with DFU.
View Article and Find Full Text PDFHuman amniotic membrane graft removal and histopathologic evaluation following closure of a full thickness macular hole.
Am J Ophthalmol Case Rep
March 2025
University of Florida, Department of Ophthalmology, USA.
Purpose: Human amniotic membrane (hAM) grafts have been used to close persistent macular holes in recent years. The results from these surgeries are promising with improved closure rate and vision. However, there is lack of data for what happens to these membranes and how long the tissue should remain inside the patient's eyes.
View Article and Find Full Text PDFClinical Outcomes and Complications in Complex Closures Under Local Anaesthesia Post-Mohs Surgery.
J Cutan Med Surg
January 2025
Department of Dermatology, University of California San Diego, San Diego, CA, USA.
Background: Mohs micrographic surgery offers high cure rates of cutaneous malignancies, but surgeons are often faced with large and complicated defects after tumour removal.
Objectives: To assess the safety and complication rates of large flaps and grafts (measuring ≥30 cm) and larger complex linear closures (CLC, ≥12.5 cm, as defined by the American Medical Association Current Procedural Terminology code set), when performed under local anaesthesia.
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