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Application of Monte Carlo simulation and artificial neural network model to probabilistic health risk assessment in fluoride-endemic areas.
Heliyon
December 2024
Department of Computer Science and Engineering, Anand Engineering College, Agra, India.
Groundwater contamination with fluoride is a considerable public health concern that affects millions of people worldwide. The rapid growth of urbanization has led to increase in groundwater contamination. The health risk assessment focuses on both acute and chronic health consequences as it investigates the extent and effects of fluoride exposure through contaminated groundwater.
View Article and Find Full Text PDFThe potential of urinary miR-200c-3p as a biomarker of fluorosis in rats.
Ecotoxicol Environ Saf
January 2025
Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province & Ministry of Health (23618504), Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang Province 150081, China. Electronic address:
Fluorine is a strong oxidizing element and excessive intake can have harmful effects, particularly on the body's calcified tissues. Recent studies have demonstrated a link between miRNA and fluorosis. This study aimed to evaluate the time-dose-effect relationship of miR-200c-3p in plasma, urine and cartilage of rats with drinking water fluorosis, and to explore its potential as a biomarker.
View Article and Find Full Text PDFNon-carcinogenic health risks of fluoride exposure in minors based on national surveillance in China, 2014 and 2018.
Sci Rep
December 2024
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, 150081, Heilongjiang, China.
High fluoride concentrations in groundwater represent a substantial global public health concern. In China, over 70 million individuals suffer from drinking water fluorosis. This study reports national surveillance data in 2014 and 2018, dividing affected areas into six regions.
View Article and Find Full Text PDFGeochemical evolution, geostatistical mapping and machine learning predictive modeling of groundwater fluoride: a case study of western Balochistan, Quetta.
Environ Geochem Health
December 2024
State Key Joint Laboratory of Environment Simulation and Pollution Control, School of Environment, Beijing Normal University, Beijing, 100875, China.
Around 2.6 billion people are at risk of tooth carries and fluorosis worldwide. Quetta is the worst affected district in Balochistan plateau.
View Article and Find Full Text PDFHydrogeochemical characteristics, source distribution, and health risk of high-fluoride groundwater in Swabi, Pakistan.
Environ Monit Assess
December 2024
National Centre of Excellence in Geology, University of Peshawar, Peshawar, 25130, Pakistan.
Article Synopsis
- The paper assesses fluoride pollution in drinking water sources in Swabi, Pakistan, highlighting its severe impact on human health, particularly fluorosis.
- It involved collecting and analyzing 126 groundwater and 18 surface water samples, revealing that 72.2% of groundwater samples exceeded WHO's safe fluoride limit.
- The study identified key factors contributing to fluoride enrichment in the aquifer, including natural processes and human activities, emphasizing the need for improved water management to protect local communities from health risks associated with high fluoride levels.
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