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Background: Lipomas can occur almost anywhere in the body, but they are exceptionally rare in the retroperitoneal region. While lipomas are common in adults, they are quite uncommon in children. Even among adults, retroperitoneal lipomas are not frequently encountered.

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Unusual hand tumor: A case report.

Radiol Case Rep

February 2025

Orthopedic and Trauma Department, Fattouma Bourguiba University Hospital, Monastir, Tunisia.

Adipose tumors are dominated by lipomas, but other rarer entities may be encountered such as hibernoma which is a benign tumor that develops from brown fat. The thigh is the preferred location for hibernomas, but the tumor can appear in other areas. The upper limb is a rare localization and there is only 1 case of hibernoma on the hand already reported in the English literature.

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Article Synopsis
  • Lipomatous tumors are the most common soft tissue neoplasms, and distinguishing between benign lipomas and more serious atypical lipomatous tumors requires accurate diagnostic methods, including MDM2/CDK4 immunostaining.
  • In a study involving 109 patients, only a small fraction of those diagnosed with atypical tumors tested positive for MDM2, indicating that traditional morphological diagnoses may be unreliable.
  • The study highlighted that certain clinical features, such as older patient age and larger tumor size, could help identify potential atypical tumors, even though the overall accuracy of the diagnostic methods assessed was not very high.
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Background: Lipomas and atypical lipomatous tumors or well-differentiated liposarcomas (ALTs/WDLs), pose a diagnostic challenge due to their overlapping clinical and imaging features. Accurate differentiation is crucial as treatment strategies differ significantly between benign lipomas and malignant ALTs/WDLs. In recent years, medical imaging techniques have shown promise in distinguishing lipomas from ALTs/WDLs by providing enhanced visualization and assessment of various imaging parameters.

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Infiltrating lipomas are a rare form of lipomas exhibiting unusual clinical behavior. We report a case of an adipocytic tumor of a 31-year-old male diagnosed with an infiltrating lipoma in the right submandibular region. It exhibits unusual clinical features such as invasion into surrounding structures, posing significant diagnostic challenges.

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