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PNEUMATOSIS CYSTOIDES INTESTINALIS. | LitMetric

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Pneumatosis intestinalis (PI) is a rare but potentially serious gastrointestinal condition with diverse clinical presentations. Pneumatosis intestinalis is identified by the presence of gas in the extraluminal intestinal wall and is further subclassified into benign pneumatosis intestinalis (BPI) and life-threatening pneumatosis intestinalis (LTPI). Prompt and accurate diagnosis, often aided by imaging studies, is crucial to guide appropriate management.

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Background: Acute mesenteric ischemia is a life-threatening disease. Intrasplenic gas is an extremely rare finding in such cases.

Case Summary: We report a case of a 79-year-old woman with a history of end-stage renal disease on hemodialysis for approximately 20 years, type 2 diabetes mellitus, and atrial fibrillation who presented with two days of epigastric pain.

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Purpose: Pneumatosis intestinalis (PI) is a rare but significant side effect associated with the use of alpha-glucosidase inhibitor (αGI) in the treatment of diabetes. This study aims to analyze the clinical features of PI induced by αGIs in patients with type 2 diabetes mellitus.

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Pneumatosis intestinalis in systemic sclerosis: navigating diagnostic and therapeutic challenges.

ANZ J Surg

February 2025

Upper Gastrointestinal Surgery Unit, Eastern Health, Melbourne, Victoria, Australia.

Background: Pneumatosis intestinalis, characterised by the presence of intramural bowel gas, is a radiological finding with varied clinical implications, ranging from incidental detection to severe underlying pathology, including bowel ischaemia or perforation. Its association with systemic sclerosis, a connective tissue disorder, remains rare and poorly understood, presenting unique diagnostic and therapeutic challenges.

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Background: Pneumatosis intestinalis (PI) is a rare radiological finding that may be associated with various diseases. In the neonatal period, it is considered pathognomonic for necrotizing enterocolitis (NEC). Cow's milk protein allergy (CMA) is the main cause of allergy especially in term infants appearing following breastfeeding or consumption of milk-based formulas.

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