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Evaluating the Acceptance and Usability of an Independent, Noncommercial Search Engine for Medical Information: Cross-Sectional Questionnaire Study and User Behavior Tracking Analysis.
JMIR Hum Factors
January 2025
Institute of General Practice, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Background: The internet is a key source of health information, but the quality of content from popular search engines varies, posing challenges for users-especially those with low health or digital health literacy. To address this, the "tala-med" search engine was developed in 2020 to provide access to high-quality, evidence-based content. It prioritizes German health websites based on trustworthiness, recency, user-friendliness, and comprehensibility, offering category-based filters while ensuring privacy by avoiding data collection and advertisements.
View Article and Find Full Text PDFClassification and characteristics of bacterial glycosaminoglycan lyases, and their therapeutic and experimental applications.
J Cell Sci
January 2025
National Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology and State Key Laboratory of Microbial Technology, Shandong University, 72 Binhai Rd, Qingdao, 266237, People's Republic of China.
Glycosaminoglycans (GAGs), as animal polysaccharides, are linked to proteins to form various types of proteoglycans. Bacterial GAG lyases are not only essential enzymes that spoilage bacteria use for the degradation of GAGs, but also valuable tools for investigating the biological function and potential therapeutic applications of GAGs. The ongoing discovery and characterization of novel GAG lyases has identified an increasing number of lyases suitable for functional studies and other applications involving GAGs, which include oligosaccharide sequencing, detection and removal of specific glycan chains, clinical drug development and the design of novel biomaterials and sensors, some of which have not yet been comprehensively summarized.
View Article and Find Full Text PDFUnderstanding identity development in context: comparing reflective and situated approaches to identity.
Front Psychol
January 2025
University College Groningen, University of Groningen, Groningen, Netherlands.
Many recent approaches to identity share a foundational similarity with ecological psychology, namely, to place identity in its context. That is, they explicitly place identity in its physical and social environments. Yet, we can distinguish at least two different approaches that diverge fundamentally with regards to the role that this "context" has in identity.
View Article and Find Full Text PDFProgress in the Study of Intratumoral Microorganisms in Hepatocellular Carcinoma.
J Hepatocell Carcinoma
January 2025
Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People's Republic of China.
The intratumoral microbiota, an integral part of liver tumors, has garnered significant attention from researchers due to its role in tumor development regulation and impact on cancer treatment. Intratumoral microorganism not only influences tumorigenesis and progression, but also serves as potential biomarkers and targets for tumor therapy. Targeted manipulation of these microorganisms holds great promise for personalized liver cancer treatment.
View Article and Find Full Text PDFComparisons of Physicians', Nurses', and Social Welfare Professionals' Experiences With Participation in Information System Development: Cross-Sectional Survey Study.
JMIR Hum Factors
January 2025
Department of Computer Science, School of Science, Aalto University, Espoo, Finland.
Background: The integration of health care and social welfare services together with the consolidation of health care information systems (HISs) and client information systems (CISs) has become a timely topic. Despite this development, there is a scarcity of systematic research on physicians', registered nurses' (RNs) and social welfare professionals' (SWPs) experiences of participating in the development of HISs and CISs.
Objective: This study aimed to examine how physicians, RNs and SWPs experience collaboration with HIS or CIS vendors, and what kinds of end users have participated in HIS or CIS development.
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