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Interventions for managing medication-related osteonecrosis of the jaw.
Cochrane Database Syst Rev
July 2022
Institute of Clinical Pharmacology, Immanuel Klinik Rüdersdorf, Brandenburg Medical School Theodor Fontane, Rüdersdorf, Germany.
Background: Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse reaction experienced by some individuals to certain medicines commonly used in the treatment of cancer and osteoporosis (e.g. bisphosphonates, denosumab, and antiangiogenic agents), and involves the progressive destruction of bone in the mandible or maxilla.
View Article and Find Full Text PDFNew trends in adjunctive treatment and diagnosis in medication-related osteonecrosis of the jaw: A 10-year review.
J Biol Regul Homeost Agents
February 2021
Free practitioner in Verona, Italy.
Medication-related osteonecrosis of the jaw (MRONJ) is a major disease under study for over the last twenty years. Different classifications have been proposed and many therapies for the different stages have been applied. The evolution of treatments lead to an increasingly conservative approach.
View Article and Find Full Text PDFDifferences between auto-fluorescence and tetracycline-fluorescence in medication-related osteonecrosis of the jaw-a preclinical proof of concept study in the mini-pig.
Clin Oral Investig
December 2020
Department of Oral and Maxillofacial Surgery, Ludwig-Maximilians University of Munich, Lindwurmstr. 2a, D-80336, Munich, Germany.
Objectives: Fluorescence-guided bone surgery is a well-established technique in the treatment of medication-related osteonecrosis of the jaw. No histopathological evidence for bone auto-fluorescence is currently available, and thus, any differences from tetracycline-fluorescence remain unclear. Therefore, the goals of this study were to find out if macroscopic and histological differences occur between the auto- and tetracycline-fluorescence in the delineation of viable and necrotic jawbone in the mini-pig.
View Article and Find Full Text PDFTreatment and posttreatment effects of a novel magnetic palatal expansion appliance with reactivation system in dogs.
Am J Orthod Dentofacial Orthop
February 2020
Department of Orthodontics, Affiliated Stomatological Hospital of Nanchang University, Stomatological and Biomedical Key Laboratory of Jiangxi Province, Nanchang, Jiangxi, China. Electronic address:
Introduction: This study aimed to compare the effects of a novel magnetic palatal expansion appliance (MPEA) during the expansion and maintenance period with that of a screw expansion appliance.
Methods: Based on previous research, the MPEA had a reactivation system that was modified for a broader working range and more stable expansion. Thirty-six male beagle dogs were assigned to a magnetic expansion (ME; n = 12), screwed expansion (SE; n = 12) or control (n = 12) group.
Interventions for managing medication-related osteonecrosis of the jaw.
Cochrane Database Syst Rev
October 2017
Institute of Pharmacology of Natural Products & Clinical Pharmacology, Ulm University, Helmholtzstr. 20, Ulm, Germany, 89081.
Background: Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse reaction experienced by some individuals to certain medicines commonly used in the treatment of cancer and osteoporosis (e.g. bisphosphonates, denosumab and antiangiogenic agents) and involves the progressive destruction of bone in the mandible or maxilla.
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