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Targetoid skin lesions in a newborn: a case of erythema multiforme.
Oxf Med Case Reports
November 2024
Pediatric Department, Dr. Thabet Thabet Hospital, Tulkarm P508, Palestine.
Erythema multiforme (EM) is an immune-mediated condition that manifests as targetoid skin lesions and can be triggered by various factors, including infections and vaccinations. This case report describes a 41-day-old full-term male infant who developed widespread annular, bullseye-shaped erythematous skin lesions one week after receiving the Bacillus Calmette-Guérin (BCG) vaccination. The infant, exclusively breastfed and without a significant past medical history, presented with these lesions but no associated systemic symptoms.
View Article and Find Full Text PDFAn Infant With Kawasaki Disease: A Case Report and Literature Review.
Cureus
July 2024
Department of Paediatrics, Shaoxing Keqiao Women and Children's Hospital, Shaoxing, CHN.
Kawasaki disease (KD) is the leading cause of acquired heart disease in children in developed countries. Delayed treatment can lead to coronary artery (CA) abnormalities, potentially causing myocardial ischemia, infarction, and death. Younger age is a risk factor for developing bilateral large CA aneurysms in KD patients.
View Article and Find Full Text PDFClinico-Laboratory Profile of Tuberculides: An Experience at a Tertiary Care Centre from Chandigarh, India.
Indian J Dermatol
April 2024
From the Department of Dermatology, Venereology and Leprology, Government Medical College and Hospital, Chandigarh, Punjab, India.
Article Synopsis
- Tuberculides are immune reactions to tuberculosis that occur in healthy individuals, and this study focuses on their characteristics and treatment responses in a North Indian healthcare center.
- Analyzing clinical records from 2000 to 2019, the study identified 34 patients with tuberculides, with lichen scrofulosorum being the most prevalent type, followed by other forms like erythema nodosum.
- The findings highlight that tuberculides can indicate hidden tuberculosis infections, aiding in early diagnosis and effective treatment with a standard six-month anti-tubercular therapy regimen.
Acute tenosynovitis following an accidental injection of Bacille Calmette-Guérin (BCG) in a health care worker: A case report.
Infect Prev Pract
March 2024
Department of Infectious Disease and Infection Control, Saitama Medical University, 38 Morohongo, Moroyama, Saitama, 350-0495, Japan.
Case: A 36-year-old female healthcare worker with no past medical history, accidentally injected her flexed right middle finger with live attenuated bacillus Calmette-Guérin (BCG). Swelling and erythema around the injured area appeared two days after the needlestick injury. She was referred to the hospital and presented approximately nine days after self-inoculation.
View Article and Find Full Text PDFA Comparative Study on the Mechanism of Delayed-Type Hypersensitivity Mediated by the Recombinant Fusion Protein ESAT6-CFP10 and Purified Protein Derivative.
Int J Mol Sci
November 2023
Division of Tuberculosis Vaccine and Allergen Products, Institute of Biological Product Control, National Institutes for Food and Drug Control, Beijing 102629, China.
Article Synopsis
- PPD is a standard skin test for tuberculosis but has limitations in distinguishing between BCG vaccination and other mycobacterial infections.
- A new skin reagent, ESAT6-CFP10 (EC), shows improved sensitivity and specificity, primarily causing erythema compared to PPD's induration.
- Comparative studies found that both EC and PPD induced similar inflammatory responses and immune pathways, suggesting the potential of EC-induced erythema as a diagnostic indicator for MTB infection.
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