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Allometry of base pair specific-DNA contents in Tetrapoda.

Hereditas

August 1993

Institute of Cytology, Russian Academy of Sciences, St. Petersburg.

Cells of 82 species of Tetrapoda were stained with DNA base pair specific fluorochromes (Hoechst 33258 and olivomycin) and studied by means of flow cytometry. The genome size range was about 50-fold. The class Amphibia, which had the widest range of genome size variation (about 20-fold), exhibited linear allometry in their base pair specific DNA contents (bps-C-values), i.

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Olivomycin was used locally as 0.2% ointment (20-40 tampons) in 39 cervical cancer cases (I stage--27 patients, II--8, III--1 and IV--2 patients) and in 2 vaginal cancer cases (II stage). There was noted a visual disappearance of the neoplasm in 24 cases, the decrease up to 1/3 of initial tumor dimensions in 11 cases, up to 1/2-2/3--in 5 cases.

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