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Percutaneous US-guided Cholecystocholangiography with Microbubbles for Assessment of Infants with US Findings Equivocal for Biliary Atresia and Gallbladder Longer than 1.5 cm: A Pilot Study.

Radiology

March 2018

From the Department of Medical Ultrasonics, Institute for Diagnostic and Interventional Ultrasound (L.Y.Z., S.L.C., Y.H., X.Y.X.), Department of Pediatric Surgery (H.D.C.), and Department of Anesthesiology (Y.X.Q.), the First Affiliated Hospital, Sun Yat-Sen University, 58 Zhongshan Rd 2, Guangzhou 510080, P.R. China; and Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou, P.R. China (W.Z.).

Purpose To evaluate the feasibility of ultrasonographically (US) guided percutaneous cholecystocholangiography (PCC) for early exclusion of biliary atresia (BA) in infants suspected of having BA with equivocal US findings or indeterminate type of BA and a gallbladder longer than 1.5 cm at US. Materials and Methods This study was approved by the ethics committee; written informed parental consent was obtained.

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Purpose: To evaluate the efficacy of ultrasonographically (US)-guided percutaneous cholecystocholangiography (PCC) for early diagnosis and characterization of biliary atresia in infants with cholestatic liver disease.

Materials And Methods: Institutional review board approval was obtained for this study. Parental informed written consent was obtained.

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Background: Historically, HIDA is the initial diagnostic test in the evaluation of biliary atresia (BA). Non-excreting HIDA scans can yield false-positive results leading to negative laparotomy.

Objective: Cholestatic infants must be evaluated promptly to exclude biliary atresia (BA) and other treatable hepatic conditions.

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Purpose: Cholangiography is often crucial for establishing the definitive diagnosis in infants with prolonged jaundice. Here, we describe our protocol of using the two-hole laparoscopic technique and discuss its benefits.

Methods: 144 consecutive patients with suspected biliary atresia were included in this retrospective study.

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