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Bacterial Isolates and Their Antimicrobial Susceptibility Patterns Among Pediatric Patients with Urinary Tract Infections: A Retrospective Cross-Sectional Study at Tertiary Level in Afghanistan.
Infect Drug Resist
January 2025
Department of Pathology and Clinical Laboratory, French Medical Institute for Mother and Children (FMIC), Kabul, Afghanistan.
Introduction: The widespread use of antibiotics is a serious and alarming situation in terms of the development of antimicrobial resistance. The current study was conducted to demonstrate the types of organism isolated from the urine of patients presenting with UTI symptoms as well as their antimicrobial sensitivity spectrum.
Methodology: A descriptive cross-sectional study was conducted, and 272 positive urine cultures from children under 5 years of age with signs and symptoms of a UTI were included in the study.
Kawasaki disease (KD) is a leading cause of acquired heart disease in children, often resulting in coronary artery complications such as dilation, aneurysms, and stenosis. While intravenous immunoglobulin (IVIG) is effective in reducing immunologic inflammation, 10-15% of patients do not respond to initial therapy, and some show resistance even after two consecutive treatments. Predicting which patients will not respond to these two IVIG treatments is crucial for guiding treatment strategies and improving outcomes.
View Article and Find Full Text PDFPrevalence of urinary abnormalities in asymptomatic school going children by dipstick method.
Pak J Med Sci
December 2024
Kainat Babar, BSc. RDT. Department of Nephrology, King Edward Medical University, Lahore, Pakistan.
Article Synopsis
- * Out of 1600 children screened, 17.38% showed urinary abnormalities on initial testing, with isolated proteinuria being the most common finding (8.19%), and combined abnormalities were rare.
- * The findings highlight the importance of routine urine screenings to detect potential kidney issues in asymptomatic children, as many may have underlying conditions that go unnoticed.
Reexamining the Role of Pyuria in UTI Diagnosis.
Pediatrics
December 2024
Infectious Diseases, Nationwide Children's Hospital, Columbus, Ohio.
Accuracy of Screening Tests for the Diagnosis of Urinary Tract Infections in Young Children.
Pediatrics
December 2024
Division of Hospital Medicine, University of Cincinnati College of Medicine, Cincinnati Children's Hospital, Cincinnati, Ohio.
Background: The objective of this study was to compare the accuracy of available tests for pyuria, including newer automated tests, and to examine the implications of requiring them for the diagnosis of urinary tract infections (UTIs).
Methods: We included children between 1 and 36 months of age undergoing bladder catheterization for suspected UTIs who presented to 1 of 3 pediatric centers. Using a positive urine culture result as the reference standard, we compared the sensitivity of 5 modalities for assessing pyuria at the cutoffs most often used clinically for detecting children with a positive culture result: leukocyte esterase on a dipstick, white blood cell (WBC) count on manual microscopy with and without using a hemocytometer, automated WBC enumeration using flow cytometry, and automated WBC enumeration using digital imaging with particle recognition.
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