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Where Does the Proton Go? Structure and Dynamics of Hydrogen-Bond Switching in Aminophosphine Chalcogenides.
Angew Chem Int Ed Engl
January 2025
University of Regensburg, Faculty of Chemistry and Pharmacy, Institute of Inorganic Chemistry, Universitätsstraße 31, D-93053, Regensburg, GERMANY.
Aminophosphates are the focus of research on prebiotic phosphorylation chemistry. Their bifunctional nature also makes them a powerful class of organocatalysts. However, the structural chemistry and dynamics of proton-binding in phosphorylation and organocatalytic mechanisms are still not fully understood.
View Article and Find Full Text PDFPagHCF106 negatively regulates drought stress tolerance in poplar (Populus alba × Populus glandulosa) by modulating stomatal aperture.
Tree Physiol
January 2025
Institute of Soil and Water Conservation, Northwest A&F University, Yangling 712100, China.
Modulation of stomatal development and movement is a promising approach for creating water-conserving plants. Here, we identified and characterized the PagHCF106 gene of poplar (Populus alba × Populus glandulosa). The PagHCF106 protein localized predominantly to the chloroplast, and the PagHCF106 gene exhibited tissue-specific expression pattern.
View Article and Find Full Text PDFExploring ferroptosis and miRNAs: implications for cancer modulation and therapy.
Mol Cell Biochem
January 2025
Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box: 14115-154, Tehran, Iran.
Ferroptosis is a novel, iron-dependent form of non-apoptotic cell death characterized by the accumulation of lipid reactive oxygen species (ROS) and mitochondrial shrinkage. It is closely associated with the onset and progression of various diseases, especially cancer, at all stages, making it a key focus of research for developing therapeutic strategies. Numerous studies have explored the role of microRNAs (miRNAs) in regulating ferroptosis by modulating the expression of critical genes involved in iron metabolism and lipid peroxidation.
View Article and Find Full Text PDFNew records on autogenic behavior among populations of Ornithodoros fonsecai (Labruna and Venzal, 2009) (Ixodida: Argasidae) from northeastern Brazil.
Vet Res Commun
January 2025
Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, USP, São Paulo, SP, Brazil.
Ornithodoros fonsecai is an argasid tick that is endemic to Brazil. The autogeny (the oviposition without a blood meal) can be facultative or obligatory in female ticks of the family Argasidae. The present study reports new records on the facultative autogeny among populations of O.
View Article and Find Full Text PDFThe NmpRSTU multi-component signaling system of regulates expression of an oxygen utilization regulon.
J Bacteriol
January 2025
Department of Microbiology, University of Wisconsin-La Crosse, La Crosse, Wisconsin, USA.
Unlabelled: has numerous two-component signaling systems (TCSs), many of which regulate the complex social behaviors of this soil bacterium. A subset of TCSs consists of NtrC-like response regulators (RRs) and their cognate histidine sensor kinases (SKs). We have previously demonstrated that a multi-component, phosphorelay TCS named NmpRSTU plays a role in social motility.
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