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Identification of HPV16 Lineages in South African and Mozambican Women with Normal and Abnormal Cervical Cytology.
Viruses
August 2024
Division of Medical Virology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town 7925, South Africa.
Background: Human papillomavirus 16 (HPV16) is an oncogenic virus responsible for the majority of invasive cervical cancer cases worldwide. Due to genetic modifications, some variants are more oncogenic than others. We analysed the HPV16 phylogeny in HPV16-positive cervical Desoxyribonucleic Acid (DNA) samples collected from South African and Mozambican women to detect the circulating lineages.
View Article and Find Full Text PDF"Deoxy" to be or "Desoxy" not to be-a century-old tale in the history of DNA nomenclature.
J Bacteriol
February 2024
Department of Biotechnology, Indian Institute of Technology Hyderabad, Sangareddy, Telangana, India.
This commentary discusses a comprehensive history of the first-ever use of pertinent words directly related to DNA, such as desoxyribose, deoxyribose, desoxyribonucleic acid, and deoxyribonucleic acid. With almost 100 years of the identification and nomenclature of desoxyribose sugar and desoxyribonucleic acid, the term "desoxy" continues to see limited use. We hope that whenever young researchers come across the sporadic occurrence of "desoxy" in any published text, they will not consider it a mistake.
View Article and Find Full Text PDFDonor/recipient origin of lung cancer after lung transplantation by DNA short tandem repeat analysis.
Front Oncol
September 2023
Department of Thoracic Surgery and Lung Transplantation, Foch Hospital, Suresnes, France.
Background: Lung cancer is more common in posttransplant recipients than in the general population. The objective of this study was to examine the chimerism donor/recipient cell origin of graft cancer in recipients of lung transplant.
Methods: A retrospective chart review was conducted at Foch Hospital for all lung transplantations from 1989 to 2020.
Sperm Dysfunction in the Testes and Epididymides due to Overweight and Obesity Is Not Caused by Oxidative Stress.
Int J Endocrinol
October 2022
Departamento de Biología de La Reproducción, Universidad Autónoma Metropolitana, Iztapalapa, Ciudad de México 09340, Mexico.
Obesity is a condition that has been linked to male infertility. The current hypothesis regarding the cause of infertility is that sperm are highly sensitive to reactive oxygen species (ROS) during spermatogenesis in the testes and transit through the epididymides, so the increase in ROS brought on by obesity could cause oxidative stress. The aim of this study was to evaluate whether the activity of the enzymes catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GPX) is capable of counteracting oxidative stress in sperm.
View Article and Find Full Text PDFAnaplastic ganglioglioma-A diagnosis comprising several distinct tumour types.
Neuropathol Appl Neurobiol
December 2022
Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.
Aims: Anaplastic ganglioglioma is a rare tumour, and diagnosis has been based on histological criteria. The 5th edition of the World Health Organization Classification of Tumours of the Central Nervous System (CNS WHO) does not list anaplastic ganglioglioma as a distinct diagnosis due to lack of molecular data in previous publications. We retrospectively compiled a cohort of 54 histologically diagnosed anaplastic gangliogliomas to explore whether the molecular profiles of these tumours represent a separate type or resolve into other entities.
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