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Hydration of 3-Methyl-1,2,3-butanetricarboxylic Acid Evidenced by Matrix-Isolation Infrared Spectroscopy.
J Phys Chem A
January 2025
Institut des Sciences Moléculaires, UMR CNRS 5255, Univ. Bordeaux, Talence cedex F-33405, France.
The hydration mechanism of 3-methyl-1,2,3-butanetricarboxylic acid (MBTCA), a relevant marker of secondary organic aerosol formation from the atmospheric oxidation of α-pinene, has been investigated using the matrix-isolation infrared spectroscopy technique. The experimental results were supported by theoretical calculations. Monomers of MBTCA and heterocomplexes MBTCA-(HO) were identified.
View Article and Find Full Text PDFAnti-Dyslipidemic Potential of Sulfated Glycosaminoglycan from Rock Oyster Saccostrea cucullata: An in vivo study.
Chem Biol Interact
January 2025
Department of Veterinary Pathology, College of Veterinary and Animal Sciences, Mannuthy 680651, Thrissur, Kerala; Veterinary and Animal Sciences University.
The rock oyster, Saccostrea cucullata, native to the Indo-Pacific region, is renowned for its nutritional and therapeutic benefits. A sulfated glycosaminoglycan (SCP-2) with β-(1→3)-GlcNSp and α-(1→4)-GlcAp as recurring units isolated from S. cucullata.
View Article and Find Full Text PDFChemical Characterization and Antimicrobial Activity of Green Propolis from the Brazilian Caatinga Biome.
Plants (Basel)
December 2024
National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.
Green propolis, particularly from the unique flora of the Brazilian Caatinga biome, has gained significant interest due to its diverse chemical composition and biological activities. This study focuses on the chemical characterization and antimicrobial evaluation of Caatinga green propolis. Twelve compounds were isolated through different chromatographic techniques, including flavanones (naringenin, 7--methyleriodictyol, sakuranetin), flavones (hispidulin, cirsimaritin), flavonols (quercetin, quercetin-3-methyl ether, kaempferol, 6-methoxykaempferol, viscosine, penduletin), and one chalcone (kukulkanin B).
View Article and Find Full Text PDFViscosol Treatment Ameliorates Insulin-Mediated Regulation of Dyslipidemia, Hepatic Steatosis, and Lipid Metabolism by Targeting PTP1B in Type-2 Diabetic Mice Model.
Int J Endocrinol
December 2024
Department of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Type 2 diabetes mellitus (T2DM), a metabolic disorder, has the hallmarks of persistent hyperglycemia, insulin resistance, and dyslipidemia. Protein-tyrosine phosphatase 1B (PTP1B) was found to be overexpressed in many tissues in the case of T2DM and involved in the negative regulation of insulin signaling. So, PTP1B inhibition can act as a therapeutic target for T2DM.
View Article and Find Full Text PDFNatural Saponins on Cholesterol-Related Diseases: Treatment and Mechanism.
Phytother Res
January 2025
School of Pharmacy, Minzu University of China, Beijing, China.
Saponins are compounds composed of lipophilic aglycones linked to hydrophilic sugars. Natural saponins are isolated from plants and some Marine organisms. As important cholesterol-lowering drugs, natural saponins have attracted wide attention for their therapeutic potential in a variety of cholesterol-related metabolic diseases.
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