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J Appl Clin Med Phys
January 2025
Medical Physics Section, OHS Department, Hamad Medical Corporation, Doha, Qatar.
Purpose: To evaluate image quality (IQ) of for-processing (raw) and for-presentation (clinical) radiography images, under different exposure conditions and digital image post-processing algorithms, using a phantom that enables multiple detection tasks.
Methods: A modified version of the radiography phantom described in the IAEA Human Health Series No. 39 publication was constructed, incorporating six additional Aluminum (Al) targets of thicknesses both smaller and larger than the standard one.
J Biophotonics
January 2025
The Richard and Loan Hill Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, Illinois, USA.
The use of photoacoustic brain imaging for hemorrhage detection holds significant clinical importance. This study focuses on the performance of sensitivity and detection capabilities of a single-element scanning system, considering the remarkable signal-to-noise ratio of photoacoustic signals generated by a single-element transducer. By employing blood vessel-like phantoms and ex vivo brain phantoms, we demonstrated the superior efficacy of the single-element scanning method over the transducer array system in the context of brain hemorrhage detection.
View Article and Find Full Text PDFBackground/objectives: Bone marrow (BM) adipocytes are critical in progressing solid tumor metastases and hematological malignancies across pediatric to aging populations. Single-point biopsies remain the gold standard for monitoring BM diseases, including hematologic malignancies, but are limited in capturing the full complexity of loco-regional and global BM microenvironments. Non-invasive imaging techniques like Magnetic Resonance Imaging (MRI), could offer valuable alternatives for real-time evaluation of BM diseases in both preclinical translational and clinical studies.
View Article and Find Full Text PDFCureus
December 2024
Neurological Surgery, Jersey Shore Medical Center, Neptune, USA.
Introduction The Synaptive magnetic resonance imaging (MRI) system (Synaptive Medical, Toronto, Canada) is a midfield 0.5 T head-only scanner for imaging the head and neck in adults and pediatrics. The system received US FDA and Health Canada clearance for clinical use in 2020.
View Article and Find Full Text PDFTech Innov Patient Support Radiat Oncol
March 2025
Mount Vernon Cancer Centre, Northwood, United Kingdom.
Brachytherapy is a key treatment for gynaecological malignancies, delivering high doses to the tumour volume whilst sparing nearby normal tissues due to its steep dose gradient. Accuracy is imperative as small shifts can lead to clinically significant under- or over-dosing of the target volume or organs at risk (OARs), respectively. Independent verification of dose delivered during brachytherapy is not routinely performed but it is important to identify gross errors and define action thresholds to guide inter-fraction treatment decisions.
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