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GeneXpert MTB/RIF Ultra in Pediatric Tuberculosis: How Disease Characteristics Modify Test Performances.
Curr Pediatr Rev
January 2025
Department of Health Sciences, University of Florence, Florence, Italy.
Introduction: The diagnosis of pediatric tuberculosis (TB) is challenging, due to the lower sensitivity of microbiological tests, such as culture and microscopy, compared to their performance in adult cases. Guidelines have introduced molecular tests, including GeneXpert MTB/ RIF and GeneXpert MTB/RIF Ultra. These tests use a real-time polymerase chain reaction method and provide information on M.
View Article and Find Full Text PDFLoad-bearing capacity of screw-retained fixed dental prostheses made of monolithic zirconia on different abutment designs and abutment-free implant connection.
J Dent
January 2025
Senior Research and Teaching Assistant, Clinic of Reconstructive Dentistry, Center for Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland. Electronic address:
Objectives: A new abutment-free implant connection allows for direct screwing of FDPs on implants to avoid complications caused by cement rests or screw loosening, which may affect to screw torque and load distribution. The objective of this study was to test the initial (Fi) and final failure (Ff) loads and torque changes of abutment-free monolithic zirconia CAD-CAM fixed dental prostheses (FDPs) compared to titanium FDPs on different abutment designs.
Methods: Three-unit screw-retained FDPs (n=50) on two implants (n=100) were divided into groups (n=10) based on the implant-abutment connection and material of the supra-structure: (1) abutment-free monolithic CAD-CAM zirconia FDP (Abut-free-Zr), (2) abutment-free veneered titanium FDPs (Abut-free-Ti), (3) monolithic zirconia FDPs with titanium base abutments (Zr-Ti-Base), (4) monolithic zirconia FDPs on multi-unit abutments (Zr-MU), (5) veneered titanium FDP on multi-unit abutments (Ti-MU).
Estrogen receptor positivity in stromal cells of the tumor bed predicts the response to neoadjuvant chemotherapy for breast carcinoma.
Breast Cancer Res Treat
January 2025
Department of Pathology, Istanbul Faculty of Medicine, Istanbul University, 34390, Faith, Istanbul, Turkey.
Purpose: This study aimed to determine estrogen receptor (ER) expression in stromal cells in postchemotherapy tumor bed (PCTB) and its relationship with tumor regression and tumor characteristics.
Methods: The study included 490 breast cancer patients who received neoadjuvant chemotherapy (NAC). We performed ER in stromal cells in all resection specimens and available pre-treatment core biopsy materials of 299 patients immunohistochemically.
Insecticide resistance mutations of Anopheles species in the Republic of Korea.
PLoS Negl Trop Dis
January 2025
Department of Biology, College of Natural Sciences, Kyungpook National University, Daegu, Republic of Korea.
The number of reported malaria cases transmitted by Anopheles mosquitoes in the Republic of Korea (ROK) increased from 420 in 2022 to 746 in 2023, a 77.6% increase. Eight Anopheles species are currently reported in the ROK, including six species belonging to the Anopheles Hyrcanus Group and one species each belonging to the Barbirostris Group and Lindesayi Group.
View Article and Find Full Text PDFExternal Auditory Canal Transillumination-Guided Middle Fossa Approaches: An Anatomical Feasibility Study.
Oper Neurosurg (Hagerstown)
January 2025
Department of Neurosurgery, Yeditepe University School of Medicine, İstanbul, Türkiye.
Background And Objectives: The middle fossa approaches are tremendously versatile for treating small vestibular schwannomas, selected petroclival meningiomas, midbasilar trunk aneurysms, and lesions of the petrous bone. Our aim was to localize the internal acoustic canal and safely drill the petrous apex with these approaches. This study demonstrates a new method to locate the internal acoustic canal during surgery in the middle fossa.
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