In 16 patients with terminal renal failure aged from 21 to 74 years maintained on haemodialysis programmes for 2 to 60 months somatosensory evoked potentials were studied after stimulation of the median nerve immediately before and after haemodialysis. The central conduction time, the P 45-N 60, P 100-N 140-P 200 complexes and the P 300 wave were evaluated. The results were compared with those in 16 healthy volunteers aged 20 to 66 years. In the patients on haemodialyses the evoked somatosensory potentials of medium and long latency differed statistically significantly from those in the control group, but not direct effect of haemodialysis on these potentials was found.
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