A study of autoimmune processes in 286 patients with different clinical forms of ischemic heart disease revealed a high frequency of antibodies to "healthy myocardium" antigen in patients with non-stable stenocardia and acute myocardial infarction that may indicate acquirement of antigenic properties of the healthy myocardium. Patients with unstable stenocardia also show an increased antibody titer to vascular antigens that indicates the possible role of activation of autoimmune reactions in the mechanisms of destabilization of the clinical course of ischemic heart disease.
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