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Usefulness of Serum Biomarkers in Predicting Anastomotic Leakage After Gastrectomy.
Cancers (Basel)
January 2025
Biomedical Research Group on Biomaterials and Wound Healing (Ciber-BBN), Traslational Research and Innovation in General and Digestive Surgery (Idipaz), 28046 Madrid, Spain.
Background/objectives: Anastomotic leakage (AL) is one of the most concerning complications following gastrectomy. The aim of this study was to assess and compare the predictive accuracy of C-reactive protein (CRP), procalcitonin (PCT), the neutrophil-to-lymphocyte ratio (NLR), the platelet-to-lymphocyte ratio (PLR), fibrinogen, and the mean platelet volume (MPV) in the early diagnosis of post-gastrectomy AL.
Methods: A prospective bicentric observational study was conducted including all patients undergoing elective gastrectomy between August 2018 and December 2022.
Using right colon interposition in patients with caustic ingestion, an introduction of a new surgical technique for post-gastrectomy reconstruction: a case series.
J Med Case Rep
December 2024
Shiraz Organ Transplant Center,, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: Corrosive substance ingestion is rare but can cause severe injury, especially to the upper gastrointestinal tract, and can be a potentially fatal event. Various surgical procedures have been advocated for gastroesophageal reconstruction, but especially those using the right colon, when the ileocecal valve is preserved for gastric reconstruction, are briefly exposed in literature and have not been studied in humans by controlled studies. Using the right colon is believed to be beneficial because of the anti-reflux mechanism of the ileocecal valve.
View Article and Find Full Text PDFHelicobacter Pylori Infection as the Predominant High-Risk Factor for Gastric Cancer Recurrence Post-Gastrectomy: An 8-Year Multicenter Retrospective Study.
Int J Gen Med
October 2024
Department of General Surgery, Wuxi Medical Center of Nanjing Medical University, Wuxi, People's Republic of China.
Purpose: The reappearance of gastric cancer, a frequent postoperative complication following radical gastric cancer surgery, substantially impacts the near-term and far-reaching medical outlook of patients. The objective of this research was to create a machine learning algorithm that could recognize high-risk factors for gastric cancer recurrence and anticipate the correlation between gastric cancer recurrence and Helicobacter pylori (H. pylori) infection.
View Article and Find Full Text PDFObjectives: The number of elderly people with stomach cancer is increasing; therefore, minimally invasive surgical treatments are required. Elderly patients have multiple comorbidities and are prone to postoperative weight loss, nutritional disorders, Postgastrectomy syndrome (PGS), and decreased quality of life (QOL). Total gastrectomy is particularly associated with these complications, although aboral-pouch creation reportedly improves the condition by compensating for lost reservoir capacity.
View Article and Find Full Text PDFComparison of proximal gastrectomy and total gastrectomy in proximal gastric cancer: a meta-analysis of postoperative health condition using the PGSAS-45.
BMC Cancer
October 2024
Department of Traditional Chinese Medicine, Jiangxi Maternal and Child Health Hospital, Nanchang, 330006, Jiangxi, China.
Article Synopsis
- The study compares the effects of proximal gastrectomy (PG) and total gastrectomy (TG) on postoperative health in patients with proximal gastric cancer (PGC).
- It analyzes data from six studies and finds that PG leads to better health outcomes, including fewer reflux symptoms, less weight loss, and reduced dietary dissatisfaction compared to TG.
- The conclusion suggests that while PG improves postoperative quality of life without negatively affecting surgical outcomes, more rigorous trials are needed to solidify these findings for clinical decisions.
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