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Catastrophic spontaneous spinal epidural hematoma following thrombolysis: An intersection of neurosurgical and cardiological challenges - An institutional experience.
J Craniovertebr Junction Spine
September 2024
Department of Neurosurgery, Smt. NHL Municipal Medical College, Ahmedabad, Gujarat, India.
Catastrophic spontaneous spinal epidural hematoma (SSEH) following thrombolysis poses a complex intersection of neurosurgical and cardiological challenges. This case report presents the institutional experience of a 66-year-old female who developed rapid-onset compressive myelopathy after thrombolysis for inferior wall myocardial infarction with injection streptokinase. SSEH, although rare, demands prompt recognition due to its potential for permanent neurologic injury and mortality.
View Article and Find Full Text PDFEfficacy and Safety of Thrombolysis in COVID-19 Related ARDS.
Recent Adv Antiinfect Drug Discov
June 2023
Department of Biochemistry, All India Institute of Medical Sciences Bhopal, 5015 Type 5 Quarters AIIMS Campus, Bhopal, India.
Introduction: COVID-19 causes significant pulmonary microthrombi in some individuals, leading to ARDS and death. Thrombolysis could be an effective approach in some patients with severe ARDS. We describe our experience with the usage of thrombolytic agents in critically ill COVID-19 patients who were in worsening respiratory failure.
View Article and Find Full Text PDFIntrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion.
Case Rep Pulmonol
October 2021
Department of Internal Medicine, Salmaniya Medical Complex, Manama, Bahrain.
Intrapleural thrombolytics have shown promising results in complicated parapneumonic pleural effusions reducing the need for surgical interventions. Until now, studies have evaluated primarily streptokinase, urokinase, and recently, alteplase. In this case series, we share our experience with tenecteplase-a tissue-specific plasminogen activator in 15 patients.
View Article and Find Full Text PDFThe Use of Chronic Total Occlusion (CTO) Wires for Perforation of Atretic Pulmonary Valve; Two Centers Experience.
Pediatr Cardiol
June 2021
Department of Pediatric Cardiology, Istanbul Health Scıence University, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Education and Research Hospital, Istasyonmahallesi Turgut Özal Bulvarı Küçükçekmece, 34303, Istanbul, Turkey.
Pulmonary valve atresia with intact ventricular septum (PA-IVS) can be treated either surgically or transcatheterly for eligible patients. Perforation of pulmonary valves using chronic total occlusion (CTO) guidewires has been reported as an alternative to radiofrequency (RF) perforation. We sought to report our experience with CTO guidewires for perforation of atretic pulmonary valves and subsequent balloon dilatation (with or without patent ductus arteriosus stenting) in patients with PA-IVS from two centers.
View Article and Find Full Text PDFStreptokinase in a COVID-19-positive patient with STEMI in a PPCI centre: a local experience.
BMJ Case Rep
January 2021
Department of Medicine, Section of Cardiology, Aga Khan University Hospital, Karachi, Pakistan.
Primary percutaneous coronary intervention is the recommended modality of treatment for acute ST-elevation myocardial infarction (STEMI). However, different countries now have different consensus about treatment of patients with STEMI during the COVID-19 pandemic. In this report, we describe a case of SARS-CoV-2-positive patient admitted with pneumonia.
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