Energy metabolism and microsomal oxidation in the liver of meadow mice caught near a source of technogenic pollution (0.5 km from the enterprise) were studied for 2 years for their peculiarities. Intensification of oxidative processes of succinic acid in the liver mitochondria and a tendency to a decrease of glycolysis in the liver homogenates were observed. Under conditions of technogenic pollution in liver of animals the level of lipid peroxidation and rate of aniline metabolism increase. Activation of the processes of aminopyrine metabolism took place in the meadow mice liver only for one season. The next year the rate of aminopyrine metabolism in the animals liver was lower. This is explained by the system inhibition under the effect of technogenic factors. Therefore, the investigation of biochemical indices is used to indicate the unfavourable effect of technogenic factors in the natural populations of small rodents.
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