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Alzheimers Dement
December 2024
University of Pennsylvania, Philadelphia, PA, USA.
Background: Histopathological analysis of autopsied brains is the gold standard of diagnosis in neurodegenerative disorders. Co-registered histology and MRI scans aid in understanding pathology and structural features. Previous studies focused on the medial temporal lobe (MTL) for atrophy patterns in phosphorylated tau (p-tau) pathology and in whole hemisphere scans with contralateral semi-quantitative p-tau measures.
View Article and Find Full Text PDFComparison of Biocompatibility of 3D-Printed Ceramic and Titanium in Micropig Ankle Hemiarthroplasty.
Biomedicines
November 2024
Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.
Background: Ankle arthritis is a common degenerative disease that progresses as cartilage damage in the lower tibia and upper talus progresses, resulting in loss of joint function. In addition to typical arthritis, there is also structural bone loss in the talus due to diseases such as talar avascular necrosis. Total talus replacement surgery is the procedure of choice in end-stage ankle arthritis and consists of a tibial, talar component and an insert.
View Article and Find Full Text PDFRapid versus slow degeneration and complications of biomaterials in patients with congenital heart disease.
Cardiovasc Pathol
December 2024
University Hospital Muenster, Department of Cardiothoracic Surgery, Muenster, Germany.
Objectives: Re-operations due to material degeneration carry a burden for patients with congenital heart disease (CHD). The study aim was to compare rapid vs. slow degeneration of biomaterials in CHD patients.
View Article and Find Full Text PDFHistological evaluation of the regenerative potential of injectable hyaluronic acid hydrogel or collagen with blood clot as scaffolds during revascularization of immature necrotic dog's teeth.
Open Vet J
November 2024
Department of Basic Oral Medical Sciences, College of Dentistry, Qassim University, Buraydah, Saudi Arabia.
Background: Regenerative endodontics' primary objective is to establish a favorable environment in the root canal by removing infection, providing a sturdy scaffold, and sealing the apical end of the tooth tightly. These actions should promote pulp regeneration and root development.
Aim: This study evaluated histologically the regenerative potential of injectable hyaluronic acid (HA) hydrogel or collagen with blood clot as scaffolds during revascularization of immature necrotic dog's teeth.
Evaluating tumour budding could improve the new grading system for lung adenocarcinoma.
Lung Cancer
December 2024
Cancer Center and Heart and Lung Center, University of Helsinki and Helsinki University Hospital, Haartmaninkatu 4, 00029 HUS Helsinki, Finland.
Objectives: To study the prognostic significance of tumour budding (TB) compared with the grading of lung adenocarcinoma (LAC).
Materials And Methods: The postoperative haematoxylin and eosin-stained histological slices of 207 surgically treated LAC patients were retrospectively reviewed by a lung pathologist. Two groups were formed from the cohort: the high-grade TB group (≥10 buds) and low-grade TB group (0-9 buds).
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