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Imaging of Pulmonary Vasculitis.
Radiol Clin North Am
March 2025
Cardiopulmonary Imaging Section, Department of Radiology, University of Alabama at Birmingham, JTN 361, 619 19th Street South, Birmingham, AL 35294, USA. Electronic address:
This review will describe various disease processes resulting in pulmonary vasculitis. The clinical and imaging findings in these diseases often overlap with diffuse alveolar hemorrhage secondary to pulmonary capillaritis, a common manifestation in many of these diseases. A multidisciplinary approach is important for the correct diagnosis of these diseases, and this review will highlight the important imaging findings that radiologists need to be aware of to aid in this diagnostic process.
View Article and Find Full Text PDFAtypical initial presentations of Sjogren's syndrome: a case series.
J Pak Med Assoc
January 2025
Department of Rheumatology, Shalamar Institute of Health Sciences, Lahore, Pakistan.
Primary Sjogren's syndrome (pSS) typically presents with Sicca symptoms xerostomia and xeropthalmia. This study highlights atypical presentations of Primary Sjogren's syndrome posing diagnostic and therapeutic challenges. Four female patients (median age 30 years, IQR = 15.
View Article and Find Full Text PDFHistological pattern of non-infectious thoracic aortitis impacts mortality.
J Autoimmun
January 2025
Sorbonne Universités, Department of Internal Medicine and Clinical Immunology, Centre de Référence des Maladies Auto-Immunes Systémiques Rares, Centre de Référence des Maladies Auto-Inflammatoires et de l'Amylose Inflammatoire (CEREMAIA), F-75013, Paris, France; INSERM, UMR_S 959, F-75013, Paris, France; DMU 3ID, AP-HP, Groupe Hospitalier Pitié-Salpêtrière, France.
Background: Non-infectious aortitis encompasses various histological patterns, but their specific cardiovascular outcomes remain unclear.
Objective: To evaluate the mortality associated with non-infectious surgical thoracic aortitis.
Methods: This retrospective multicenter study included patients who underwent thoracic aortic surgery and had histological evidence of aortitis.
Proteomic profiling of the large-vessel vasculitis spectrum identifies shared signatures of innate immune activation and stromal remodelling.
Arthritis Rheumatol
January 2025
Department of Immunology and inflammation, Imperial College London, UK.
Background: Takayasu arteritis (TAK) and giant cell arteritis (GCA), the most common forms of large-vessel vasculitis (LVV), can result in serious morbidity. Understanding the molecular basis of LVV should aid in developing better biomarkers and treatments.
Methods: Plasma proteomic profiling of 184 proteins was performed in two cohorts.
A 51-Year-Old Man With Dyspnea and a Pulmonary Nodule.
Chest
January 2025
State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
A 51-year-old man presented with chest tightness, exertional dyspnea, and occasional chest pain for 2 years. The patient visited his local hospital initially, and CT scan revealed a ground glass opacity (GGO) located in the right upper lobe (Fig 1A). He was diagnosed as having pulmonary infection and treated with levofloxacin for 12 days.
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