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Ont Health Technol Assess Ser
January 2025
Background: Chronic neuropathic pain is a major health problem that adversely affects people's physical and mental well-being, as well as their quality of life. Percutaneous peripheral nerve stimulation (PNS) may offer a minimally invasive option earlier in the treatment continuum for adults with chronic neuropathic pain that is refractory to conventional medical management. We conducted a health technology assessment of PNS for adults with chronic neuropathic pain, which included an evaluation of effectiveness, safety, cost-effectiveness, the budget impact of publicly funding PNS, and patient preferences and values.
View Article and Find Full Text PDFEur J Med Res
January 2025
Department of Otolaryngology, Affiliated Hospital of Hebei University, 212th Yuhua Road, Baoding, Hebei, China.
The patient's body temperature significantly fluctuates, affected by factors, including anesthesia. The ideal temperature monitoring method that is suitable for perioperative application is of great significance for identifying hypothermia and malignant hyperthermia early, as well as for guiding intraoperative temperature protection. This study aims to compare the cutaneous zero-heat-flux (ZHF) thermometer application in general anesthesia using the infrared tympanic measurement as a reference.
View Article and Find Full Text PDFBMC Anesthesiol
January 2025
Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Background: Postoperative nausea and vomiting (PONV) are common complications following general anesthesia, particularly in gynecological laparoscopic surgeries. This study aims to evaluate the effect of intraoperative noise isolation on PONV incidence.
Method: This single-center, prospective, randomized controlled trial will enroll 192 adult patients undergoing laparoscopic gynecological surgery.
PLoS One
January 2025
Department of Anesthesiology, Henan Provincial Chest Hospital & Chest Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Background: Postoperative nausea and vomiting (PONV) is a common complication of general anesthesia. This affects 30-80% of patients, and leads to discomfort and extended hospital stays. The effectiveness of penehyclidine for preventing PONV remains a subject of debate in the literature.
View Article and Find Full Text PDFPLoS One
January 2025
Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Pre-established anaesthetic protocols in animal models might unexpectedly interfere with the main outcome of scientific projects and therefore they need to account for the specific research goals. We aimed to optimize the anaesthetic protocol and animal handling strategies in a diabetes-related-study exemplifying how the anaesthetic approach must be adjusted for individual research targets. Aachen minipigs were used as a model to test long-lasting skin glucose sensors for diabetic human patients.
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