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Cost-effective track and trace technology for poor-quality chemotherapeutic pharmaceuticals in resource-limited countries: a review of the Chemotherapeutic Paper Analytical Device.
Front Med Technol
November 2024
Department of Pharmaceutical Chemistry, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Poor-quality medicines (substandard or counterfeit) can lead to treatment failure. There is a vast global imbalance in cancer treatment outcomes due to the difficulty of accessing quality chemotherapeutic products. Early diagnosis of cancer brings more hope for curative treatment of cancer and increases the demand for chemotherapeutic products.
View Article and Find Full Text PDFEvidence generation throughout paediatric medicines life cycle: findings from collaborative work between European Medicines Agency (EMA) and EUnetHTA on use of extrapolation.
Br J Pharmacol
February 2025
Dental and Pharmaceutical Benefits Agency (Tandvårds-och läkemedelsförmånsverket, TLV), Stockholm, Sweden.
Drug development for children presents unique challenges and is highly regulated. Novel approaches, such as the use of extrapolation to address, for example, the need to avoid unethical studies, whilst supporting robust evidence generation have been developed in support of benefit/risk considerations by regulatory authorities. This is only one step in the decision-making process towards access, which in Europe also includes health technology assessment (HTA) bodies.
View Article and Find Full Text PDFDual dye-labeled aptamers for detection of dichlorvos using ratiometric fluorescence resonance energy transfer.
Anal Chim Acta
November 2024
State Key Laboratory of Toxicology and Medical Countermeasures, Laboratory of Toxicant Analysis, Academy of Military Medical Sciences, Beijing, 100850, China. Electronic address:
Article Synopsis
- Dichlorvos (DDVP) is a highly toxic pesticide, making the monitoring of its residues in the environment and human health crucial, but traditional detection methods are cumbersome and not suitable for on-site testing.
- The study involved the development and testing of two aptamer probes, finding that DV55 was more effective than DV65 for detecting DDVP, with a fast reaction time of just 5 minutes and a detection range of 0-100 μM.
- The research highlights the potential of these dual-labeled aptamer probes as a portable, efficient method for rapid on-site detection of DDVP, showing promising results for future applications in pesticide monitoring.
Withdrawn: Recent Developments in Nanomaterial Drug Delivery and Upgrading Treatment of Cardiovascular Disease.
Curr Pharm Des
November 2023
Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India.
Unlabelled: Since the idea and content of this article have been found to be similar to one of the published articles titled “Recent Developments in Nanomaterials-Based Drug Delivery and Upgrades in the Treatment of Cardiovascular Diseases, 2022, Volume 23, Issue 3”, the article has been withdrawn from the journal “Current Pharmaceutical Design”, due to the unethical practice of the author. Bentham Science apologizes to the readers of the journal for any inconvenience this might have caused. The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.
View Article and Find Full Text PDFAntenatal interventions to address harmful behaviors and psychosocial risk factors in the prevention of low birth weight.
Am J Clin Nutr
June 2023
Center for Child, Adolescent and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Background: Risk factors related to the harmful behaviors, psychosocial wellbeing, and socio-economic circumstances in the lives of pregnant women can lead to adverse birth outcomes, including low birth weight (LBW).
Objective: This systematic search and review aims to provide a comparative evidence synthesis on the effect of eleven antenatal interventions targeted to address psychosocial risk factors on adverse birth outcomes.
Methods: We searched MEDLINE, Embase, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials and CINAHL Complete between March 2020 and May 2020.
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