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Fertility in transgender and gender diverse people: systematic review of the effects of gender-affirming hormones on reproductive organs and fertility.
Hum Reprod Update
January 2025
Amsterdam UMC, Location Vrije Universiteit Amsterdam, Centre of Expertise on Gender Dysphoria, Amsterdam, The Netherlands.
Background: Transgender and gender diverse (TGD) people seek gender-affirming care at any age to manage gender identities or expressions that differ from their birth gender. Gender-affirming hormone treatment (GAHT) and gender-affirming surgery may alter reproductive function and/or anatomy, limiting future reproductive options to varying degrees, if individuals desire to either give birth or become a biological parent.
Objective And Rationale: TGD people increasingly pursue help for their reproductive questions, including fertility, fertility preservation, active desire for children, and future options.
Pure yolk sac ovarian tumor in a young female-Case report with brief review of literature.
SAGE Open Med Case Rep
November 2024
Department of Pathology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Yolk sac tumors (YSTs) of the ovary are the second most common primitive germ cell tumors accounting for 20% of malignant ovarian germ cell tumors. They are derived from primitive germ cells of the embryonic gonad and can undergo germinomatous or embryonic differentiation. They commonly affect women in the reproductive age group but have a favorable prognosis due to chemosensitivity.
View Article and Find Full Text PDFInvestigation of the morphological and histological features of the testes of pigeon () in pre-puberty and post-puberty.
Open Vet J
September 2024
College of Education for Pure Science Ibn Al Haitham, University of Baghdad, Baghdad, Iraq.
Article Synopsis
- - The study aimed to analyze the testicular morphology and histology of local pigeons at different maturation stages to gain insight into their reproductive health.
- - Results showed that the testis retains an oval shape and exhibits size differences between the left and right sides, with significant histological changes occurring from pre-puberty (smaller with collapsed tubules) to post-puberty (larger, closely packed tubules with mature cells).
- - The findings emphasize the importance of understanding testicular structure changes in pigeons to assess male reproductive system complexity and the role of sex hormones and various cell types in testicular function.
The effect of methylphenidate on the reproductive function of female rats.
J Obstet Gynaecol Res
January 2025
Department of Pharmacology, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan, Turkey.
Aim: Research on the effects of methylphenidate on female fertility is limited. This study evaluated the effects of methylphenidate on reproductive function, oxidants, antioxidants, proinflammatory cytokines, prolactin, and cortisol in female rats.
Methods: Forty-eight albino Wistar female rats were divided into four groups consisting of 12 rats, which were given pure water orally once daily for 7 days (HG-1), 10 mg/kg methylphenidate orally once daily for 7 days (MP-1), pure water orally once daily for 30 days (HG-2), and 10 mg/kg methylphenidate orally once daily for 30 days (MP-2).
Transplantation of human umbilical cord-derived mesenchymal stem cells improves age-related ovarian functional decline via regulating the local renin-angiotensin system on inflammation and oxidative stress.
Stem Cell Res Ther
October 2024
Reproductive Medicine Center, First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Background: Age-related reproductive aging is a natural and irreversible physiological process, and delaying childbearing is increasingly common all over the world. Transplantation of mesenchymal stem cells (MSCs) is considered a new and effective therapy to restore ovarian function, but the relevant mechanisms remain unclear. Recently, it has been found that there is a local Renin-angiotensin system (RAS) in human ovary and it plays a key role.
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