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Press-Fit Bone-Anchored Prosthesis for Individuals with Transtibial Amputation.
JBJS Essent Surg Tech
May 2024
Radboud University Medical Center, Nijmegen, The Netherlands.
Background: This video article describes the use of bone-anchored prostheses for patients with transtibial amputations, most often resulting from trauma, infection, or dysvascular disease. Large studies have shown that about half of all patients with a socket-suspended artificial limb experience limited mobility and limited prosthesis use because of socket-related problems. These problems occur at the socket-residual limb interface as a result of a painful and unstable connection, leading to an asymmetrical gait and subsequent pelvic and back pain.
View Article and Find Full Text PDFParenterally administered amino acids decrease acute mortality in fasting patients with aspiration pneumonia: A retrospective study.
Clin Nutr ESPEN
January 2025
Department of Respiratory Medicine, Hamamatsu Medical Center, Japan.
Background & Aims: To prevent food aspiration, numerous patients with aspiration pneumonia are restricted from eating early during their hospital stay. Although they receive parenteral nutrition (PN) on a fasting regimen, the optimal dose and composition remain unknown. The current study aimed to investigate whether PN with amino acids (AA) affects 30-day mortality of patients with aspiration pneumonia.
View Article and Find Full Text PDFComprehensive Extractables and Leachables Sensitization Analysis and Practical Application of a Risk-Based Approach to Sensitization Assessment for Parenteral Drug Products.
Regul Toxicol Pharmacol
January 2025
Faegre Drinker Biddle & Reath LLP, Washington, DC, USA.
The Extractables and Leachables Safety Information Exchange (ELSIE) Consortium added to the sensitization potency analysis of Parris et al. (2023) by including the Product Quality Research Institute (PQRI) extractable and leachable dataset (Johnson et al., 2024; Product Quality Research Institute, 2021).
View Article and Find Full Text PDFRecurrence of skin and soft tissue infections: identifying risk factors and treatment strategies.
Curr Opin Infect Dis
January 2025
Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna.
Purpose Of Review: Recurrent skin and soft tissue infections (RSSTIs) are challenging for the clinicians due to morbidity and healthcare-related costs. Here, we review updates on risk factors and management.
Recent Findings: RSSTIs rates range between 7 and 45%.
Health policy to address disease-related malnutrition: a scoping review.
BMJ Nutr Prev Health
December 2024
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Background: Health policies promote optimal care, yet policies that address disease-related malnutrition (DRM) are lacking. The purpose of this study was to conduct a scoping review to identify literature on existing and planned policy to address DRM in children or adults and explore the settings, contexts and actors of DRM policy.
Methods: A search strategy comprising DRM and policy keywords was applied to eight databases on 24 February 2023.
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