A method for the extraction of an antihistamine-like substance (or substances) from human tissues is described. The method has demonstrated the presence of this active principle(s) in a large variety of human tissues, so far without exception. The substance(s) has a wide range of activity in antagonizing the in vitro effects of histamine, 5-hydroxytryptamine and bradykinin and the Schultz-Dale reaction on the guinea-pig ileum and rat uterus preparations.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1703880 | PMC |
| http://dx.doi.org/10.1111/j.1476-5381.1963.tb02009.x | DOI Listing |
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