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The shaping of the human intestinal microbiota starts during the intrauterine period and continues through the subsequent stages of extrauterine life. The microbiota plays a significant role in the predisposition and development of immune diseases, as well as various inflammatory processes. Importantly, the proper colonization of the fetal digestive system is influenced by maternal microbiota, the method of pregnancy completion and the further formation of the microbiota.
View Article and Find Full Text PDFRapid detection of carbapenem-resistant Escherichia coli and carbapenem-resistant Klebsiella pneumoniae in positive blood cultures via MALDI-TOF MS and tree-based machine learning models.
BMC Microbiol
January 2025
Department of Clinical Laboratory, Zhejiang Rong Jun Hospital, Jiaxing, 314000, China.
Background: Bloodstream infection (BSI) is a systemic infection that predisposes individuals to sepsis and multiple organ dysfunction syndrome. Early identification of infectious agents and determination of drug-resistant phenotypes can help patients with BSI receive timely, effective, and targeted treatment and improve their survival. This study was based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), Decision Tree (DT), Random Forest (RF), Gradient Boosting Machine (GBM), eXtreme Gradient Boosting (XGBoost), and Extremely Randomized Trees (ERT) models were constructed to classify carbapenem-resistant Escherichia coli (CREC) and carbapenem-resistant Klebsiella pneumoniae (CRKP).
View Article and Find Full Text PDF[Research progress in tolerance of petroleum hydrocarbon pollutant-degrading strains].
Sheng Wu Gong Cheng Xue Bao
January 2025
Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Petroleum hydrocarbon pollution has become one of the global environmental problems, posing a serious threat to the environment and human health. Microbial remediation plays an important role in the remediation of petroleum hydrocarbon-contaminated environment. Nevertheless, the stress factors present in the environment polluted by petroleum hydrocarbons limit the effectiveness of microbial remediation.
View Article and Find Full Text PDFExploring Logical Intuition in Base-Rate Problems Using the Instructional Manipulation Paradigm.
Behav Sci (Basel)
January 2025
School of Psychology, Jiangxi Normal University, Nanchang 330022, China.
The default-interventionist model of dual-process theories proposes that stereotype descriptions in base-rate problems are processed using Type 1 processing, while the evaluation of base rates depends on Type 2 processing. The logical intuition view posits that people can process base-rate information using Type 1 processing. This study examined the logical intuition view using the instructional manipulation paradigm.
View Article and Find Full Text PDFComprehension of gut microbiota and microRNAs may contribute to the development of innovative treatment tactics against metabolic disorders and psychiatric disorders.
Int J Physiol Pathophysiol Pharmacol
December 2024
Department of Food Science and Nutrition, Nara Women's University Kita-Uoya Nishimachi, Nara 630-8506, Japan.
Metabolic syndrome is a group of pathological disorders increasing the risk of serious diseases including cardiovascular disease, stroke, type 2 diabetes. Global widespread of the metabolic syndrome has put a heavy social burden. Interestingly, a crucial link between the metabolic syndrome and a psychiatric disorder may frequently coexist, in which certain shared mechanisms might play a role for the pathogenesis.
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