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Article Synopsis
  • Actinomycosis is a rare bacterial infection caused by Actinomyces species, particularly Actinomyces israeli, and can present as a solid mass in the colon, simulating cancer.
  • A 68-year-old man with multiple health issues was diagnosed with an obstructive mass in his sigmoid colon after presenting with abdominal pain; surgery confirmed the infection and involved a total colectomy.
  • Although abdominal actinomycosis can confuse doctors and lead to unnecessary surgeries, it's usually treatable with antibiotics, and complicated cases may require both surgery and continued antibiotic treatment for complete recovery.
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Article Synopsis
  • * Despite normal inflammatory markers and negative traditional tests, metagenomic next-generation sequencing (mNGS) identified Actinomyces odontolyticus as the culprit pathogen in her lungs.
  • * Treatment with high doses of penicillin G successfully resolved her symptoms and significantly improved her lung condition, highlighting mNGS as an effective tool for diagnosing rare infections.
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Lyme disease and Whipple's disease: a comprehensive review for the rheumatologist.

Adv Rheumatol

March 2024

Rheumatology Division, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, 455- 3º andar- sala 3192 Cerqueira Cesar, CEP:01246-903, Sao Paulo, SP, Brazil.

Article Synopsis
  • Lyme disease and Whipple's disease are rare but important because they can cause joint pain that looks like other diseases.
  • * Lyme disease usually affects big joints about six months after a skin rash occurs, while Whipple’s disease can cause joint problems years before stomach issues appear.
  • * Both diseases can be confused with more common conditions, and knowing where they occur can help doctors make the right diagnosis.
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A 63-year-old man was admitted to the hospital for nausea, vomiting, and right flank pain. He was found to have septic emboli in multiple organs secondary to aortic valve endocarditis. He was started on broad-spectrum antibiotics and underwent valve replacement.

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A man in his 50s, with a history of night sweats and weight loss, presented acutely with dyspnoea and chest pain. Imaging revealed right middle lobe consolidation and a large pericardial effusion. The diagnosis of actinomycosis was made using endobronchial ultrasound-guided sampling from the pericardial effusion.

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