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Infectious endocarditis (IE) is an infection of the heart's endothelial lining, often stemming from an underlying bacteremia. High-risk populations include intravenous substance users, individuals with structural heart disease, those with intravascular devices, and those with prosthetic heart valves. In the emergency department, IE is often suspected in patients with a fever, known risk factors, and unexplained systemic symptoms due to systemic thromboemboli.

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A Rare Case of Recurrent Takotsubo Cardiomyopathy Complicated by Thromboemboli.

J Investig Med High Impact Case Rep

May 2024

Mount Sinai Morningside and BronxCare Health System, NY, USA.

Article Synopsis
  • Takotsubo syndrome (TTS) is a temporary heart condition characterized by ballooning of the heart's apex, often triggered by emotional or physical stress and associated with factors like sympathetic stimulation and certain medications.
  • Diagnosis includes checking specific heart activity patterns and using imaging techniques like angiography to rule out other heart issues.
  • A case report highlighted a 61-year-old woman with a history of TTS who experienced a recurrence during hospitalization, emphasizing the need for quick diagnosis and treatment to improve patient outcomes, especially in critical situations.
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Introduction: Acute mechanical thrombectomy (MT) is the preferred treatment for large vessel occlusion-related stroke. Histopathological research on the obtained occlusive embolic thrombus may provide information regarding the aetiology and pathology of the lesion to predict prognosis and propose possible future acute ischaemic stroke therapy.

Methods: A total of 75 consecutive patients who presented to the Amphia Hospital with acute large vessel occlusion-related stroke and underwent MT were included in the study.

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The influence of blood composition and loading frequency on the behavior of embolus analogs.

J Mech Behav Biomed Mater

April 2023

Mechanical, Aerospace, And Biomedical Engineering, University of Tennessee, Knoxville, TN, USA. Electronic address:

In cases of acute ischemic stroke (AIS), mechanical thrombectomy (MT) can be used to directly remove lodged thromboemboli. Despite improvements in patient outcomes, one of the key factors affecting MT success is the mechanical properties of the occlusive thrombus. Therefore, the goal of this study was to investigate the viscoelastic properties of embolus analogs (EAs) and determine the influence of EA hematocrit and loading frequency.

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Thrombosis and bleeding in hematological malignancy.

Best Pract Res Clin Haematol

March 2022

Department of Medicine, Washington University St. Louis School of Medicine, Saint Louis, Missouri, USA; Department of Medicine, Saint Louis Veterans Administration Medical Center, Saint Louis, Missouri, USA. Electronic address:

Venous (VTE) and arterial (ATE) thromboemboli are a leading cause of morbidity and mortality in patients with cancer. Patients with hematological malignancies are at an exceptionally high risk of both VTE and ATE. This risk varies based on patient- and disease-specific risk factors and can be predicted using risk prediction models for some types of hematological malignancies.

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