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Pak J Pharm Sci
March 2025
Orthopedics Department of Beijing Xiaotangshan Hospital, Xiaotangshan Town, Changping District, Beijing, China.
Caltrate D is a commonly used drug in the treatment of postmenopausal osteoporosis (PMOP), but the effect of single application is not ideal. Therefore, to investigate the eight section brocade therapy combined with caltrate D effect in preventing and treating PMOP. From January 2021 to June 2022, 110 postmenopausal women with decreased bone mass were selected and randomized into group A (n = 54) and group B (n = 56).
View Article and Find Full Text PDFGynecological endocrinology (also known as endocrine gynecology) is the unique integrative area of reproductive medicine. It was established circa 50 years ago due to breakthrough discoveries in the gynecology, endocrinology and internal medicine. According to Russian legislation there is no such specialization as endocrinologist-gynecologist but there is a lack of appropriate doctors due to complicated residenture post-diploma system in Russian national healthcare.
View Article and Find Full Text PDFJ Matern Fetal Neonatal Med
December 2025
Department of Gynecology and Obstetrics, Xuanwu Hospital, Capital Medical University, Beijing, China.
Objective: Unexplained Recurrent Spontaneous Abortion (RSA) impacts the physical and psychological well-being of women of reproductive age. This study aimed to reveal the potential mechanisms behind unexplained RSA from the perspective of glucose and lipid metabolic profiles before conception and their relationship with immune, coagulation, and inflammatory markers.
Methods: A retrospective analysis was conducted on 100 patients with unexplained recurrent spontaneous abortion at our gynecology department from June 2022 to June 2023.
Cancer Cell Int
March 2025
Department of Obstetrics and Gynecology, Zhongda Hospital Jiangbei Branch, School of Medicine, Southeast University, Nanjing, 210048, Jiangsu, China.
This study aimed to determine the molecular mechanisms underlying immune escape in ovarian cancer. Samples of ovarian cancer were used to explore the regulatory pathways involved in the malignant phenotype. Tumor cell models with different levels of factor expression were constructed via transfection, and their regulation was determined through investigation of protein expressions.
View Article and Find Full Text PDFEur J Med Res
March 2025
Department of Rehabilitation, School of Nursing, Jilin University, Changchun, 130021, China.
Background: The rise in endometrial cancer rates globally calls for advanced diagnostic methods and new biomarkers. CPA4, known for its role in cancer development, has not yet been studied in relation to endometrial cancer, making it a promising research avenue.
Methods: We analyzed CPA4's mRNA expression using data from TCGA and GEO databases and validated these findings with 116 clinical samples through immunohistochemical analysis.
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