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Inverse dose protraction effects of high-LET radiation: evidence and significance.
Mutat Res Rev Mutat Res
January 2025
Radiation Epidemiology Branch, National Cancer Institute, MD 20892-9778, USA; Faculty of Health, Science and Technology, Oxford Brookes University, Headington Campus, OX3 0BP, UK.
Biological effects of ionizing radiation vary with radiation quality, which is often expressed as the amount of energy deposited per unit length, i.e., linear energy transfer (LET).
View Article and Find Full Text PDFA Prospective Study of a Custom-Made Eco-Friendly Thyroid Shield: A Breakthrough in Radiation Protection.
Cureus
December 2024
Department of Oral Medicine and Radiology, Drs Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Vijayawada, IND.
Background The thyroid gland is the most susceptible organ to radiation during the exposure of teeth because the thyroid area appears to be within the primary beam, and the dose levels are relatively high even after using collimation. This study aims to develop an eco-friendly thyroid shield by reusing lead foils from intra-oral periapical radiographic films and evaluate its effectiveness in intraoral radiography. Methods A total of 16 patients undergoing endodontic procedures who gave written consent to participate in the study were included and divided into four categories: anterior, canine, premolar, and molar.
View Article and Find Full Text PDFInverse dose protraction effects of low-LET radiation: evidence and significance.
Mutat Res Rev Mutat Res
January 2025
Radiation Epidemiology Branch, National Cancer Institute, MD 20892-9778, USA; Faculty of Health, Science and Technology, Oxford Brookes University, Headington Campus, OX3 0BP, UK.
Biological effects of ionizing radiation vary not merely with total dose but also with temporal dose distribution. Sparing dose protraction effects, in which dose protraction reduces effects of radiation have widely been accepted and generally assumed in radiation protection, particularly for stochastic effects (e.g.
View Article and Find Full Text PDFGenetic algorithm optimized BP neural network for fast reconstruction of three-dimensional radiation field.
Appl Radiat Isot
January 2025
School of Physics and Electronic Engineering, Sichuan University of Science and Engineering, Yibin, 644005, China.
The three-dimensional radiation field is an important database reflecting the radioactivity distribution in a nuclear facility. It is of great significance to accurately and quickly grasp the radiation dose field distribution to implement radiation protection. Presently, majority of radiation field reconstruction algorithms concentrate on two-dimensional reconstruction and can only measure on a regular grid.
View Article and Find Full Text PDFRevisiting the safety limit in magnetic nanoparticle hyperthermia: insights from eddy current induced heating.
Phys Med Biol
January 2025
Department of Physics, Aristotle University of Thessaloniki, University Campus, Thessaloniki, 54124, GREECE.
Magnetic nanoparticle hyperthermia (MNH) emerges as a promising therapeutic strategy for cancer treatment, leveraging alternating magnetic fields (AMFs) to induce localized heating through magnetic nanoparticles (MNPs). However, the interaction of AMFs with biological tissues leads to non-specific heating caused by eddy currents, triggering thermoregulatory responses and complex thermal gradients throughout the body of the patient. While previous studies have implemented the Atkinson-Brezovich limit to mitigate potential harm, recent research underscores discrepancies between this threshold and clinical outcomes, necessitating a re-evaluation of this safety limit.
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