Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Effects of doxapram, prethcamide and lobeline on spirometric, blood gas and acid-base variables in healthy new-born calves.
Vet J
November 2012
Clinic of Reproductive Medicine, Vetsuisse-Faculty, University Zurich, Switzerland.
A number of drugs have been used to treat asphyxia in new-born calves and the aim of the current study was to investigate the effect of commonly-used stimulant drugs on ventilation, arterial blood gas and acid base variables. A group (n=18) of new-born (3-15 h old) calves were treated in a randomised sequence with doxapram (40 mg, IV), lobeline (5mg, IV) or prethcamide (5 mL, consisting of 375 mg crotethamide and 375 mg cropropamide, buccally). Blood and spirometric measurements, using an ultrasonic spirometer, were collected prior to and 1, 5, 15, 30, 60, 90 min after administration of each drug.
View Article and Find Full Text PDFPharmacokinetics of prethcamide following rapid intravenous injection and oral administration in rabbits.
Pol J Pharmacol Pharm
April 1986
A simple gas chromatographic method for the quantitative determination of ethyl butamide and propyl butamide, the active constituents of the analeptic drug "Prethcamide", in whole blood and tissues has been developed. The method was used to study the disposition of the compounds after iv and po administration to rabbits. The course of changes of ethyl butamide and propyl butamide concentration following rapid intravenous injection and oral administration was described by the two-compartment and one-compartment open models, respectively.
View Article and Find Full Text PDFThe efficacy of four respiratory analeptics on healthy young men in a CO2 rebreathing experiment.
Arzneimittelforschung
July 1979
Four respiratory analeptics were examined in a CO2 rebreathing experiment with increase from 0--6% in the inspiratory CO2 concentration during 30 min on 24 healthy young men. The respiratory response curves (VE/pCO2) showed a parabolic shape. They were examined on parallel shift and change of slope.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!