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Overexpression of FTO alleviates traumatic brain injury induced posttraumatic epilepsy by upregulating NR4A2 expression via m6A demethylation.
Funct Integr Genomics
January 2025
Department of Radiology, The Second Xiangya Hospital of Central South University, No. 139, Renmin Middle Road, Furong District, Changsha City, Hunan Province, 410011, China.
Post-traumatic epilepsy (PTE) is a debilitating chronic outcome of traumatic brain injury (TBI). Although FTO has been reported as a possible intervention target of TBI, its precise roles in the PTE remain incompletely understood. Here we used mild or serious mice TBI model to probe the role and molecular mechanism of FTO in PTE.
View Article and Find Full Text PDFAre neurasthenia and depression the same disease entity? An electroencephalography study.
BMC Psychiatry
January 2025
Department of Neurology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong, China.
Background: The neurasthenia-depression controversy has lasted for several decades. It is challenging to solve the argument by symptoms alone for syndrome-based disease classification. Our aim was to identify objective electroencephalography (EEG) measures that can differentiate neurasthenia from major depressive disorder (MDD).
View Article and Find Full Text PDFNo significant relationship found between spontaneous motor tempo, heartbeat, and individual alpha frequency: an analysis of internal tempos.
Sci Rep
January 2025
Department of Life Sciences, The University of Tokyo, Tokyo, Japan.
Many theories of time perception propose the existence of an internal pacemaker, and studies across behavioral, physiological, and neuroscience fields have explored this concept. Specifically, Spontaneous Motor Tempo (SMT), the most comfortable and natural tapping tempo for each individual, is thought to reflect this internal pacemaker's tempo. Changes in heart rate are also linked to time estimation, while Individual Alpha Frequency (IAF), the peak in the alpha range (8-13 Hz) observed in EEG, is reported to reflect the brain's temporal processing.
View Article and Find Full Text PDFWorking-memory load decoding model inspired by brain cognition based on cross-frequency coupling.
Brain Res Bull
January 2025
School of Life and Health Information Science and Engineering, Chongqing University of Posts and Telecommunications, Chongqing 400065, China; College of Computer Science and Technology, Chongqing University of Posts and Telecommunications, Chongqing 400065, China; Institute for Advanced Sciences, Chongqing University of Posts and Telecommunications, Chongqing 400065, China; Guangyang Bay Laboratory, Chongqing Institute for Brain and Intelligence, Chongqing 400064, China. Electronic address:
Working memory, a fundamental cognitive function of the brain, necessitates the evaluation of cognitive load intensity due to limited cognitive resources. Optimizing cognitive load can enhance task performance efficiency by preventing resource waste and overload. Therefore, identifying working memory load is an essential area of research.
View Article and Find Full Text PDFEvaluation of flavor perception of strong-aroma Baijiu based on electroencephalography (EEG) and surface electromyography (EMG) techniques.
Food Chem
January 2025
Department of Food Science & Technology, School of Agriculture & Biology, Shanghai Jiao Tong University, Shanghai 200240, China; School of Food Science and Engineering, Ningxia University, Yinchuan 750021, China. Electronic address:
This study investigates the flavor perception of strong-aroma Baijiu through physiological electrical signals, focusing on electroencephalography (EEG) and electromyography (EMG) during olfactory and gustatory evaluations. It examines how sensory qualities, especially mellowness, influence brain and muscle responses. Results showed significant differences in EEG δ and β wavebands, mainly in the frontal and temporal lobes, reflecting varying brain activities across Baijiu types.
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