The paper deals with the results of a comparative morphologic, toxicologic and biochemical study of the character of reparative processes in destructive forms of pulmonary tuberculosis, specific features of non-coordination of collagen metabolism depending on the cumulation of organochlorine and organophosphorus pesticides and in the absence of their residual quantities in the patient's body on admission to a hospital and during current antibacterial therapy. The resected and removed lungs and blood of 1063 patients were used for the study. Specific features of a tuberculosis course, the duration and effectiveness of antibacterial therapy, the character of reparative processes, characteristic features of collagen metabolism and collagenosis, the character and dissemination of residual changes due to therapy were established in the compared groups of patients.
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