An antibody precipitating urease was found in 171 out of 180 human sera. Data obtained on limited material (50 cases) suggest that the anti-urease titre is appreciably higher in the serum of patients suffering from gastric ulcer. This is a pointer towards a possible antigen-antibody mechanism in the genesis of chronic gastric ulceration.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413489PMC
http://dx.doi.org/10.1136/gut.4.4.339DOI Listing

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