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Intensive care unit patients often experience memory disturbances, including missing or delusional memories. These memory distortions can contribute to the development of psychiatric disorders, such as anxiety and depression. In addition, distorted memories may adversely affect long-term quality of life.

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Exploring delusional themes and other symptoms in first episode psychosis: A network analysis over two timepoints.

Psychiatry Res

January 2025

Department of Psychiatry, Faculty of Medicine and Health Sciences, McGill University, 1033 Pine Avenue West, Montreal, QC, , H3A 1A1, Canada; Prevention and Early Intervention Program for Psychosis, Douglas Mental Health University Institute, 6875 Blvd. LaSalle, Montreal, QC, , H4H 1R3, Canada. Electronic address:

Delusions are a defining feature of psychosis and play an important role in the conceptualization and diagnosis of psychotic disorders; however, the particular role that different delusions play in the prognosis of these disorders is not well understood. This study explored relationships between delusions and other symptoms in 674 first episode psychosis (FEP) individuals by comparing symptom networks between baseline and 12 months after intake to an early intervention service. Specifically, we (1) estimated regularized partial correlation networks at baseline and month 12, (2) identified the most central symptoms in each network, (3) identified clusters of highly connected symptoms, and (4) compared networks to examine changes in structure and connectivity.

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Surviving the 2021 heat dome with schizophrenia: A qualitative, interview-based unpacking of risks and vulnerabilities.

Soc Sci Med

December 2024

Department of Psychiatry, Faculty of Medicine, University of British Columbia, B.C. Mental Health and Substance Use Services, Provincial Health Services Authority, Vancouver, BC, Canada.

This study explores the multifaceted challenges experienced by individuals with schizophrenia during extreme heat, highlighting the interplay between individual factors, social dynamics, and environmental influences. Despite making up only 1% of the Canadian population, individuals diagnosed with schizophrenia comprised 16% (n = 97) of the deaths during the 2021 heat dome in Western Canada. However, to date, there exists scant qualitative research that explore the direct experiences and the intricacies of intersecting factors faced by individuals with schizophrenia during extreme heat events.

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Background: Phenomenological psychopathologists have recently highlighted how people with delusions experience multiple realities (delusional and non-delusional) and have suggested this double bookkeeping cannot be explained via predictive processing. Here, we present data from Kamin blocking and extinction learning that show how predictive processing might, in principle, explain a pervasive sense of dual reality.

Methods: This cross-sectional study involved three participant groups: patients with schizophrenia (SZ; n=42), healthy participants with elevated esoteric beliefs (EEB; clairaudient psychics; n=31), and heathy controls (with neither illness nor significant delusional ideation, n=62).

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In 1994, the DSM-IV added the specifier "with poor insight" to the diagnostic criteria of obsessive-compulsive disorder (OCD). The DSM-5 went one step further and now allows clinicians to diagnose OCD "with absent insight/delusional beliefs," thereby blurring the long-standing distinction between OCD and psychosis. The present study surveyed OCD experts as to their opinions on the insight specifier and the future classification of OCD.

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