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Bioactive Compounds from Propolis on Bone Homeostasis: A Narrative Review.
Antioxidants (Basel)
January 2025
Research Group on Technology Applied to Exercise Physiology-GTAFE, Health Sciences Postgraduate Program, São Francisco University, Bragança Paulista 12916-900, SP, Brazil.
This narrative review explores the potential effects of Propolis and its bioactive compounds on bone health. Propolis, a resinous product collected by bees, is renowned for its antimicrobial, anti-inflammatory, and antioxidant properties. Recent research emphasizes its positive role in osteogenesis, primarily through the modulation of osteoclast and osteoblast activity via molecular pathways.
View Article and Find Full Text PDFInfluence of the Sodium Titanate Crystal Size of Biomimetic Dental Implants on Osteoblastic Behavior: An In Vitro Study.
Biomimetics (Basel)
January 2025
DENS-ia Research Group, Faculty of Health Sciences, Miguel de Cervantes European University, C/del Padre Julio Chevalier 2, 47012 Valladolid, Spain.
Treating the surfaces of dental implants in an alkaline medium allows us to obtain microstructures of sodium titanate crystals that favor the appearance of apatite in the physiological environment, producing osteoconductive surfaces. In this research, 385 discs made of titanium used in dental implants underwent different NaOH treatments with a 6M concentration at 600 °C and cooling rates of 20, 50, 75, and 115 °C/h. Using high-resolution electron microscopy, the microstructures were observed, and the different crystal sizes were determined and compared with control samples (those without biomimetic treatment).
View Article and Find Full Text PDFPlasma-electrolytic oxidation: A rapid single step post processing approach for additively manufactured biomedical implants.
Biomater Adv
January 2025
School of Chemical Engineering, University of Birmingham, Edgbaston B15 2TT, United Kingdom. Electronic address:
Laser-powder bed fusion (PBF-LB) has enabled production of customised skeletal implants that incorporate porous lattices structures to enable bone ingrowth. However, the inherent surface roughness of PBF-LB, characterised by partially adhered particles and undulating sub-topography, remains a barrier to adoption. As such PBF-LB surfaces require several time-consuming post-processing steps, nevertheless, conventional finishing techniques are often limited by geometrical part complexity, making them unsuitable for porous PBF-LB parts.
View Article and Find Full Text PDFDifferential expression of osteoblast-like cells on self-organized titanium dioxide nanotubes.
J Dent Sci
December 2024
Division for Globalization Initiative, Liaison Center for Innovative Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.
Background/purpose: Titanium dioxide nanotube (TNT) structures have been shown to enhance the early osseointegration of dental implants. Nevertheless, the optimal nanotube diameter for promoting osteogenesis remains unclear due to variations in cell types and manufacture of nanotubes. This study aimed to evaluate the differences in MC3T3-E1 and Saos-2 cells behavior on nanotubes of varying diameters.
View Article and Find Full Text PDFIdentification of a global gene expression signature associated with the genetic risk of catastrophic fracture in iPSC-derived osteoblasts from Thoroughbred horses.
Anim Genet
February 2025
Department of Clinical Sciences and Services, Centre for Vaccinology and Regenerative Medicine, The Royal Veterinary College, Hatfield, Herts, UK.
Bone fractures are a significant problem in Thoroughbred racehorses. The risk of fracture is influenced by both genetic and environmental factors. To determine the biological processes that are affected in genetically susceptible horses, we utilised polygenic risk scoring to establish induced pluripotent stem cells (iPSCs) from horses at high and low genetic risk.
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