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Similar Publications

Benign Adult-Type Osteopetrosis with Recurrent Osteomyelitis of the Maxilla-A Rare Case Report.

Indian J Dent Res

October 2024

Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India.

Osteopetrosis, also known as marble bone disease, is a genetic condition characterised by generalised sclerosis of bones. The osteoclastic cells responsible for bone resorption are defective and nonfunctional. These patients tend to have low bone quality in spite of increased bone deposition and thus experience multiple fractures during their life span.

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Autoinflammatory Bone Diseases.

Balkan Med J

January 2025

Department of Pediatric Rheumatology, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, Türkiye.

Autoinflammatory bone diseases (AIBDs) constitute a recently identified subset of autoinflammatory diseases. These conditions are characterized by an exaggerated inflammatory response in the bones without any apparent etiology. Inflammatory bone lesions associated with AIBDs exhibit chronic inflammation, are typically culture-negative, and do not exhibit discernible microorganisms on histopathological examination.

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Oroantral fistula (OAF) represents the pathological communication between the oral cavity and maxillary sinus. This condition arises when the structural integrity of the maxillary sinus floor is compromised, resulting in a direct conduit between the sinus and the oral cavity. A less prevalent yet clinically significant contributor to the formation of OAF is chronic osteomyelitis of the maxilla.

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Article Synopsis
  • - A 61-year-old male with diabetes and hypertension experienced severe facial pain due to complications from COVID-19, including osteomyelitis affecting his frontal sinus and upper jaw.
  • - Imaging revealed thickening of the maxillary sinus and several damaging lesions in the frontal sinus, which led to brain abscesses identified through culture tests.
  • - The treatment included antibiotics and surgery (trephination and drainage), along with other medications and sessions in a hyperbaric chamber to promote healing.
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Objectives: To provide an overview of the features of patients with medication-related osteonecrosis of the jaw (MRONJ) and explore recurrence-related factors after surgery.

Materials And Methods: All pathological records of patients diagnosed with osteonecrosis or osteomyelitis of the jaw were reviewed. Only patients who had a history of use of medication related to bone turnover were included.

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