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Daniel Bovet, Nobelist: muscle relaxants in anaesthesia : The role played by two neglected protagonists.
Wien Med Wochenschr
November 2016
Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, PO Box 340 (Haartmaninkatu 4), 00029 HUS, Helsinki, Finland.
In 1957, Professor Daniel Bovet received the Nobel Prize in Physiology or Medicine for his studies on various compounds including the muscle relaxants gallamine and succinylcholine that became very useful in anaesthesia. Textbooks credit Professor Bovet for the discovery of these drugs. However, although he indeed did discover their pharmacological character, the actual syntheses were made by Ernest Fourneau and Reid Hunt, respectively; sadly, these two scientists have largely been ignored.
View Article and Find Full Text PDFThe last twenty-five years have provided a continuing success story in the achievement of satisfactory obstetric analgesia. Maternal mortality and morbidity from general anaesthesia has not decreased substantially. Mothers still run the same risk of inhalational pneumonitis and are even more likely to suffer the distressing experience of awareness.
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