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[Research advances in the transplacental transfer efficiencies of environmental pollutants].
Se Pu
January 2025
School of Public Health, Wuhan University, Wuhan 430071, China.
Industrialization has led to significant increases in the types and quantities of pollutants, with environmental pollutants widely present in various media, including the air, food, and everyday items. These pollutants can enter the human body via multiple pathways, including ingestion through food and absorption through the skin; this intrusion can disrupt the production, release, and circulation of hormones in the body, resulting in a range of illnesses that affect the reproductive, endocrine, and nervous systems. Consequently, these pollutants pose substantial risks to human health.
View Article and Find Full Text PDFCongenital and Perinatal Viral Infections: Consequences for the Mother and Fetus.
Viruses
October 2024
Feto Maternal Centre, Al Markhiya Doha, Doha P.O. Box 34181, Qatar.
Viruses are the most common congenital infections in humans and an important cause of foetal malformations, neonatal morbidity, and mortality. The effects of these infections, which are transmitted in utero (transplacentally), during childbirth or in the puerperium depend on the timing of the infections. These vary from miscarriages (usually with infections in very early pregnancy), congenital malformations (when the infections occur during organogenesis) and morbidity (with infections occurring late in pregnancy, during childbirth or after delivery).
View Article and Find Full Text PDFTrans-Placental Transfer Mechanisms of Aromatic Amine Antioxidants (AAs) and -Phenylenediamine Quinones (PPD-Qs): Evidence from Human Gestation Exposure and the Rat Uterine Perfusion Model.
Environ Sci Technol
December 2024
MOE Key Laboratory of Pollution Processes and Environmental Criteria, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China.
Aromatic amine antioxidants (AAs), as rubber additives, and their ozone photochemical oxidation products of -phenylenediamine quinone (PPD-Qs) have attracted great attention recently due to their wide environmental occurrences and toxicity. However, there is currently no research on the exposure risks during pregnancy and their trans-placental transfer mechanisms. Herein, 20 AAs and six PPD-Qs were analyzed in 60 maternal urine and fifty-six amniotic fluid samples ( = 53 pairs).
View Article and Find Full Text PDFMaternal Preconception COVID-19 Vaccination and Its Protective Effect on Infants after a Breakthrough Infection during Pregnancy.
Vaccines (Basel)
October 2024
National Clinical Research Center for Child Health and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Diseases, Children's Hospital of Chongqing Medical University, Chongqing 400015, China.
Article Synopsis
- * Conducted in Chongqing, China, the research involved 158 infants and measured levels of SARS-CoV-2 IgG and neutralizing antibodies, finding those born to vaccinated mothers with breakthrough infections had the highest antibody levels.
- * Results indicated that antibody levels declined with infant age but persisted for about four months, highlighting the importance of maternal vaccination for better infant immunity against COVID-19.
[Vaccination against respiratory syncytial virus (RSV)-For the protection of infants and older adults].
Inn Med (Heidelb)
November 2024
Institut für Internationale Gesundheit, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.
Respiratory syncytial virus (RSV) is a frequent cause of respiratory infections in all age groups. Infections in infants and older adults frequently result in severe disease and complications. There is no specific antiviral treatment against RSV.
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