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Gestational Serum Retinol Deficiency Is Associated with Enamel Hypoplasia.
J Dent Res
December 2023
Faculty of Dentistry, National University of Singapore, Singapore.
Enamel hypoplasia (EH) is a prevalent developmental defect of teeth that can result from various insults, including prenatal nutrient deficiencies. This study aimed to evaluate the association between prenatal serum retinol deficiency and EH in the deciduous teeth of offspring at 2-y of age. A cohort of 1,450 pregnant women was enrolled, and their prenatal nutritional status was assessed between 12 and 14 wk of gestation.
View Article and Find Full Text PDFFactors that affect placental retinol transfer in preterm infants and mothers with retinol deficiency.
Turk J Med Sci
April 2022
Department of Gynecology and Obstetrics, Erzurum Regional Training and Research Hospital, Erzurum, Turkey.
Background: The retinol level and retinol delivery to the placenta may vary depending on various factors involving the mother and newborn. The present study evaluates the factors affecting retinol levels in newborns and the transplacental retinol passage in preterm newborns.
Methods: In this prospective cohort study, the retinol and retinol binding protein (RBP) in the umbilical cord blood of 44 preterm infants with a gestation age of <30 weeks were studied.
Bilateral Corneal Melting in a Pediatric Patient with Severe Vitamin A Deficiency: A Case Report and Review of Literature.
Int Med Case Rep J
May 2022
Ophthalmology Department, Kabul University of Medical Science, Kabul, Afghanistan.
Background: Keratomalacia refers to an ocular destructive dryness of the cornea that results from severe vitamin A deficiency. It is an ocular condition, usually affecting both eyes. It affects infants, children and women of reproductive age.
View Article and Find Full Text PDFBilateral Keratomalacia Leading to Blindness Secondary to Diet-Induced Vitamin A Deficiency in Infants.
J Pediatr Ophthalmol Strabismus
March 2020
Vitamin A is a fat-soluble vitamin that plays an important role in the development of the immune system, and a deficiency can cause blindness associated with xerophthalmia and premature mortality. Blindness from vitamin A deficiency is avoidable if supplements such as breast milk and other food fortification are provided to neonates at the time of weaning. The authors describe two infants who presented with keratomalacia and subsequent blindness.
View Article and Find Full Text PDFOutcome of application of amniotic membrane graft in ocular surface disorders.
J Pak Med Assoc
July 2017
Department of Ophthalmology, Unit-1, Dow University of Health Sciences, Karachi.
Objective: To determine the outcome of application of amniotic graft in ocular surface disorders.
Methods: This cross-sectional study was conducted at Dow University of Health Sciences, Karachi, from January 2010 to December 2012, and comprised patients with ocular surface disorders. Patients' presenting symptoms and signs were recorded.
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