Colonic endometriosis is an uncommon lesion usually found in premenopausal women. We describe two postmenopausal women with colonic endometriosis that resulted in colonic obstruction. One of the women was receiving estrogen-replacement therapy. Colonic endometriosis in postmenopausal women may become more common as the population ages and the use of long-term estrogen-replacement therapy becomes increasingly widespread.

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