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The hydrolysis rates of many organic chemicals are accelerated under alkaline conditions by the presence of hydroxide (HO), which is typically assumed to be the predominant species contributing to base-catalyzed hydrolysis in both natural waters and laboratory buffers used in standard protocols. In this study, we demonstrated that weak bases (e.g.

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This study investigates the influence of environmental factors on the secondary metabolites of Stachyslavandulifolia Vahl., focusing on how soil properties, temperature, and precipitation affect the yield and chemical composition of its essential oils. The research was conducted in two domains within three rangelands in Mazandaran province, Iran.

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Although the comparison between two great Victorian masterminds, Sigmund Freud and Sherlock Holmes, and their respective methods, is in itself not new (see for example Ginzburg 1979, 1980; Brooks 1984; Marcus 1984; Shephard 1985; Spence 1987), it merits further investigation, as it raises important questions regarding the nature and structure of clinical evidence, clinical epistemology, and clinical narration. In this article, the author: refers both to the common cultural background of these two projects (including the of the modern world and the complicated dialog between rationality and imagination) and their common epistemological situation; analyses their and , and characterizes both Holmes and Freud as and . Their operandi are described as hermeneutical procedures, methodologically similar to Charles Sanders Peirce's .

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Imaging Biomarker Studies of Antipsychotic-Naïve First-Episode Schizophrenia in China: Progress and Future Directions.

Schizophr Bull

January 2025

Department of Radiology, and Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu 610041, China.

Background And Hypothesis: Identifying biomarkers at onset and specifying the progression over the early course of schizophrenia is critical for better understanding of illness pathophysiology and providing novel information relevant to illness prognosis and treatment selection. Studies of antipsychotic-naïve first-episode schizophrenia in China are making contributions to this goal.

Study Design: A review was conducted for how antipsychotic-naïve first-episode patients were identified and studied, the investigated biological measures, with a focus on neuroimaging, and how they extend the understanding of schizophrenia regarding the illness-related brain abnormality, treatment effect characterization and outcome prediction, and subtype discovery and patient stratification, in comparison to findings from western populations.

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Artificial intelligence technology has demonstrated remarkable diagnostic efficacy in modern biomedical image analysis. However, the practical application of artificial intelligence is significantly limited by the presence of similar pathologies among different diseases and the diversity of pathologies within the same disease. To address this issue, this paper proposes a reinforced collaborative-competitive representation classification (RCCRC) method.

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