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A novel anxiety-associated SNP identified in () is associated with decreased protein binding to nicotinic acetylcholine receptors.
Front Behav Neurosci
December 2024
Department of Biological Sciences, Lehigh University, Bethlehem, PA, United States.
Introduction: Anxiety disorders are among the most common mental illnesses in the US. An estimated 31.1% of U.
View Article and Find Full Text PDFAccidental Organophosphate Poisoning in a Patient Due to a Bed Bug Pesticide in the United Kingdom: A Case Report.
Cureus
December 2024
Emergency Medicine, North West Regional Hospital, Burnie, AUS.
Organophosphate (OP) compounds, developed during World War II, are a group of chemicals used as pesticides, insecticides and herbicides. As irreversible inhibitors of the enzyme acetylcholinesterase (AChE), they reduce anti-cholinesterase activity and therefore increase acetylcholine (ACh) levels at the neuromuscular junction (NMJ). Diazinon, the OP leading to the patient's symptoms in this report, is an amber-brown liquid that was once the most widely used insecticide in the United States of America.
View Article and Find Full Text PDFCharacterization of auditory sensation in .
Biophys Rep
December 2024
Life Sciences Institute, University of Michigan, Ann Arbor 48109, USA.
Research using the model organism nematode has greatly facilitated our understanding of sensory biology, including touch, olfaction, taste, vision and proprioception. While hearing had long been considered to be restricted to vertebrates and some arthropods, we recently discovered that is capable of sensing and responding to airborne sound in a frequency and sound source-size-dependent manner. auditory sensation occurs when airborne sound physically vibrates their external cuticle (skin) to activate the sound-sensitive mechanosensory FLP/PVD neurons via nicotinic acetylcholine receptors (nAChRs), triggering aversive phonotaxis behavior.
View Article and Find Full Text PDFInvestigating How Eating Behavior Shapes Mental Health: A Cross-Sectional Study.
Physiol Behav
January 2025
Hacettepe University, Faculty of Health Sciences, Department of Nutrition and Dietetics, Sihhiye, Ankara, Turkey. Electronic address:
This study aimed to examine the relationship between eating behavior, nutritional status and mental health. It is a cross-sectional study conducted on a sample of 360 healthy individuals aged 19-64 years. The General Health Questionnaire (GHQ-12) was used to evaluate mental health and the Three-Factor Eating Scale (TFEQ-R21) was used to assess eating behavior.
View Article and Find Full Text PDFThe role of glucocorticoid and nicotinic acetylcholine receptors in the reward-enhancing effects of nicotine in the ICSS procedure in male and female rats.
Drug Alcohol Depend
December 2024
Department of Psychiatry, University of Florida, Gainesville, FL, USA. Electronic address:
Tobacco use disorder is a chronic disorder that affects more than one billion people worldwide and causes the death of millions each year. The rewarding properties of nicotine are critical for the initiation of smoking. Previous research has shown that the activation of glucocorticoid receptors (GRs) plays a role in nicotine self-administration in rats.
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